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ProteomicsInterplay between Two Paralogous Human Silencing Hub (HuSH) Complexes in Regulating LINE-1 Element Silencing
The Human Silencing Hub (HuSH) complex is a complex that silences retrotransposable elements invertebrates. Here, we identify a second HuSH complex, designated HuSH2, which is centered aroundTASOR2, a paralog of the core TASOR protein in HuSH. Our findings reveal that HuSH and HuSH2 localize todisti...
ORGANISM(S): Homo sapiens (Human) 
2024-09-24 | PXD049085 | Pride
Human Hush complex Ip-ms 
TranscriptomicsH3K36 mutations promote sarcomagenesis through genome-wide remodeling of H3K36 and H3K27 methylation
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Drosophila melanogaster 
2016-05-13 | E-GEOD-69291 | biostudies-arrayexpress
GenomicsH3K36 mutations promote sarcomagenesis through genome-wide remodeling of H3K36 and H3K27 methylation [Ring1b_ChIP]
The goal of this study is to understand the genome-wide alterations in chromatin landscape induced by a histone mutation (H3.3K36M) derived from chondroblastomas Examination of genome-wide Ring1b distribution in cells expressing H3.3WT and H3.3K36M.
ORGANISM(S): Mus musculus 
2016-05-13 | E-GEOD-69286 | biostudies-arrayexpress
GenomicsH3K36 mutations promote sarcomagenesis through genome-wide remodeling of H3K36 and H3K27 methylation [Cbx2_ChIP]
The goal of this study is to understand the genome-wide alterations in chromatin landscape induced by a histone mutation (H3.3K36M) derived from chondroblastomas Examination of genome-wide Cbx2 distribution in cells expressing H3.3WT and H3.3K36M.
ORGANISM(S): Mus musculus 
2016-05-13 | E-GEOD-75856 | biostudies-arrayexpress
UnknownSARS-CoV-2 Omicron-B.1.1.529 leads to widespread escape from neutralizing antibody responses.
Not available
S-EPMC8723827 | biostudies-literature
UnknownOncogenic Signaling Pathways in The Cancer Genome Atlas.
Not available
S-EPMC6070353 | biostudies-literature
UnknownAnalysis of shared common genetic risk between amyotrophic lateral sclerosis and epilepsy.
Not available
S-EPMC7818383 | biostudies-literature
UnknownAzithromycin in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial.
Not available
S-EPMC7884931 | biostudies-literature
UnknownEffect of Hydroxychloroquine in Hospitalized Patients with Covid-19.
Not available
S-EPMC7556338 | biostudies-literature
UnknownConvalescent plasma in patients admitted to hospital with COVID-19 (RECOVERY): a randomised controlled, open-label, platform trial.
Not available
S-EPMC8121538 | biostudies-literature
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