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ProteomicsPhosphoproteomic profiling discriminates between myeloid and lymphoid pathotypes in early RA synovium
Background: Rheumatoid arthritis (RA) is a complex heterogenous autoimmune disease and achieving long term disease remission is an elusive goal for patients, thus implying improvement in drug targeting is necessary. Kinases are intracellular signalling mediators and key to sustaining the inflammator...
ORGANISM(S): Homo sapiens (Human) 
2024-08-08 | PXD044963 | Pride
Lc-ms/ms Mass spectrometry Label-free Phosphoproteomics 
TranscriptomicsRNA-Seq of synovial tissue biopsies from individuals with rheumatoid arthritis from the R4RA randomised clinical trial
Transcriptomic profiles of synovial biopsies of rheumatoid arthritis (RA) patients who were recruited into the R4RA randomised clinical trial. Patients were randomised to treatment with rituximab or tocilizumab. All patients fulfilled the 2010 ACR/EULAR classification criteria for RA and were eligib...
ORGANISM(S): Homo sapiens 
2022-04-26 | E-MTAB-11611 | biostudies-arrayexpress
TranscriptomicsGene expression profile of preclinical arthritis and its modulation by antigen-induced tolerance
During the course of adjuvant arthritis, maximal changes in gene expression were observed at the incubation phase. A major group of genes affected was related to immune activity. Tolerance induction by mycobacterial heat-shock protein 65 (Bhsp65), the disease-related antigen, caused upregulation of ...
ORGANISM(S): Rattus norvegicus 
2011-11-16 | E-GEOD-31314 | biostudies-arrayexpress
TranscriptomicsRNA-seq of synovial biopsies from rheumatoid arthritis patients
Synovial biopsies from rheumatoid arthritis patients were obtained and profiled using RNA-seq. Patients were stratified according to the number of swollen joints they had (SJC, swollen joint count) and divided in three groups for the differential expression analysis: None (SJC = 0), Low (1<= SJC <= ...
ORGANISM(S): Homo sapiens 
2021-04-26 | E-MTAB-6684 | biostudies-arrayexpress
UnknownA phylogeny for North American Mallocybe (Inocybaceae) and taxonomic revision of eastern North American taxa.
Not available
S-EPMC10918758 | biostudies-literature
UnknownRA-MAP, molecular immunological landscapes in early rheumatoid arthritis and healthy vaccine recipients.
Not available
S-EPMC9085807 | biostudies-literature
UnknownA novel mutation causing nephronophthisis in the Lewis polycystic kidney rat localises to a conserved RCC1 domain in Nek8.
Not available
S-EPMC3441220 | biostudies-literature
UnknownAssociation between body weight and tocilizumab effectiveness in rheumatoid arthritis: results from the BSRBR-RA.
Not available
S-EPMC11781575 | biostudies-literature
UnknownCombined effects of three independent SNPs greatly increase the risk estimate for RA at 6q23.
Not available
S-EPMC2701332 | biostudies-literature
Unknownd<sup>10</sup>s<sup>2</sup> Post-Transition Metal Anions: Identifying and Analyzing Their Dual-Mode Lewis Basicity.
Not available
S-EPMC11931533 | biostudies-literature
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