Lewis y - OmicsDI

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Genomics (131)
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Proteomics (62)
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Organisms

Homo sapiens (118)
Aerococcus urinae NBRC 15544 = CCUG 36881 (39)
Andropogon gerardi (39)
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cellular organisms (1)
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Organisms

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Repository

biostudies-arrayexpress (98)
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Tissue

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Disease

Breast cancer (2)
Colon cancer (2)
Disease free (2)
Cytomegalovirus seropositive (1)
Irritable bowel syndrome (1)
Alzheimer's disease 1 (1)
Burkitt lymphoma (1)
Influenza (1)
Periodontitis (1)
Type 2 diabetes mellitus (1)

Technology Type

Mass Spectrometry (40)
Mass spectrometry (32)
Shotgun proteomics (27)
NMR spectroscopy (13)
Bottom-up proteomics (5)
Data-dependent acquisition (5)
Mass spectrometry assay (2)
Gel-based experiment (2)
HDMSE (2)
SWATH MS (2)
Top-down proteomics (2)
ABI_SOLID, Illumina HiSeq 2000, Illumina 450K, AB 5500xl Genetic Analyzer, AB 5500 Genetic Analyzer, ILLUMINA (1)
Illumina HiSeq 2500 (ILLUMINA), AB SOLiD System (ABI_SOLID) (1)
AB SOLiD 4 System, Illumina HiSeq 2500, Illumina HiSeq 2000, AB SOLiD System 3.0 (1)
Affymetrix 6.0 (1)
ESI (1)
Affinity purification coupled with mass spectrometry proteomics (1)
Chemical cross-linking coupled with mass spectrometry proteomics (1)

Instrument Platform

Liquid Chromatography MS - negative - reverse phase (14)
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Bruker (6)
Nuclear Magnetic Resonance (NMR) - (6)
Liquid Chromatography MS - positive - hilic (6)
Q Exactive (5)
Orbitrap Eclipse (4)
LTQ Orbitrap Velos (4)
Q Exactive Plus (3)
Liquid Chromatography MS - Positive (LC-MS (Positive)) (3)
Gas Chromatography MS - positive (3)
Liquid Chromatography MS - negative - hilic (3)
NextSeq 500 (2)
Orbitrap Fusion Lumos (2)
Direct infusion MS - negative (2)
Direct infusion MS - positive (2)
Liquid Chromatography MS - negative (2)
Liquid Chromatography MS - positive (2)
GeneChip Scanner 2500 (1)
Illumina HiSeq 4000 (1)
LTQ Orbitrap (1)
MaXis (1)
Orbitrap Fusion (1)
Q Exactive HF (1)
Exactive Plus (Thermo Scientific) (1)
Q Exactive (Thermo Scientific) (1)
Gas Chromatography MS - (1)
Liquid Chromatography MS - Negative (LC-MS (Negative)) (1)
Thermo Scientific LTQ FT Ultra (1)
Gas Chromatography MS - Positive (GC-MS (Positive)) (1)

Publication Date

2011 (30)
2020 (17)
2023 (16)
2014 (15)
2022 (14)
2012 (13)
2021 (13)
2010 (11)
2024 (9)
2016 (9)
2013 (9)
2025 (9)
2018 (9)
2015 (6)
2009 (6)
2005 (6)
2007 (4)
2017 (4)
2019 (4)
2008 (3)
2026 (1)

UNIPROT ID/AC

A0A024RAN2 (2)
A0A024RC46 (2)
A0A087WTX5 (2)
A0A087WVW2 (2)
A0A087WWK8 (2)
A0A087WYL9 (2)
A0A087X130 (2)
A0A087X1V9 (2)
A0A0A0MS07 (2)
A0A0A0MS51 (2)
A0A0A0MSA7 (2)
A0A0C4DGT3 (2)
A0AVT1 (2)
A0M8Q6 (2)
A0MZ66 (2)
A0N5G5 (2)
A1L0T0 (2)
A2BFH1 (2)
A2NI60 (2)
A2NUT2 (2)
A2RU30 (2)
A4F255 (2)
A5A3E0 (2)
A5PKW4 (2)
A6NEL2 (2)
A6NGB9 (2)
A6NHL2 (2)
A6NNZ2 (2)
A7KAX9 (2)
A7XYQ1 (2)

ENSEMBL ID

ENSG00000170477 (2)

CHEBI ID

CHEBI:25017 (15)
CHEBI:16449 (14)
CHEBI:25094 (13)
CHEBI:17368 (13)
CHEBI:28044 (12)
CHEBI:27266 (12)
CHEBI:16704 (12)
CHEBI:16919 (12)
CHEBI:27897 (12)
CHEBI:30769 (12)
CHEBI:18186 (11)
CHEBI:24898 (11)
CHEBI:15428 (11)
CHEBI:7916 (11)
CHEBI:18237 (10)
CHEBI:17234 (10)
CHEBI:17568 (10)
CHEBI:16737 (10)
CHEBI:15354 (10)
CHEBI:26271 (9)
CHEBI:28300 (9)
CHEBI:16708 (9)
CHEBI:15741 (9)
CHEBI:17154 (9)
CHEBI:17750 (9)
CHEBI:15891 (9)
CHEBI:78320 (9)
CHEBI:17351 (9)
CHEBI:6650 (8)
CHEBI:15843 (8)

Metabolite Name

Hypoxanthine (8)
Linoleic acid (7)
Creatine (7)
Glycine (6)
Valine (6)
Arachidonic acid (6)
Alanine (6)
Creatinine (6)
Acetate (5)
Leucine (5)
Proline (5)
Phenylalanine (5)
Alanine (5)
Leucine (5)
Trigonelline (5)
Uracil (5)
Pantothenic acid (5)
Choline (5)
Glucose (5)
Serine (4)
Lysine (4)
Tyrosine (4)
Lactate (4)
Isoleucine (4)
Valine (4)
Pantothenate (4)
Daidzein (4)
Nicotinamide (4)
Indole (4)
Taurine (4)

First Public Date

2024 (6)
2014 (5)
2025 (2)
2021 (2)
2023 (1)

Modelling Approach

Constraint-based model (1)

Lab affiliation

Univeristy of Georgia (5)
Division of Genetic and Genomic Medicine, Department of Pediatrics, UPMC Children's Hospital of Pittsburgh, Pittsburgh, USA (3)
Molecular Biology and the Lewis-Sigler Institute for Integrative Genomics, Princeton University, USA (2)
1Department of Microbiology, University of Washington, Seattle, Washington, USA (1)
BU Bioscience, Wageningen Plant Research, Wageningen UR. the Netherlands (1)
Center for Metabolic Disease Research (CMDR) Lewis Katz School of Medicine at Temple University Medical Education and Research Building, Room 1060 3500 N. Broad Street Philadelphia, PA 19140, USA (1)
Centre for Cancer Biology, SA Pathology and the University of South Australia, Adelaide SA 5000, Australia (1)
Chemical & Biomolecular Engineering, Johns Hopkins University (1)
College of Life Sciences, Northwest University, Xi’an 710069, China (1)
Department of Anatomy and Neurobiology Virginia Commonwealth University Richmond, VA 23298-0709 USA (1)
Department of Anatomy and Neurobiology, School of Medicine, Virginia Commonwealth University, Richmond, VA USA (1)
Department of Anthropology, University of Oklahoma, USA (1)
Department of Biological Sciences, University of Arkansas, USA (1)
Department of Cell and Regenerative Biology Department of Chemistry Director of Mass Spectrometry Human Proteomics Program University of Wisconsin-Madison (1)
Department of Laboratory Medicine, Institute of Biomedicine, University of Gothenburg, Sweden. Laboratory of Clinical Chemistry, Sahlgrenska University Hospital, Gothenburg, Sweden (1)
Department of Medicine II Haematology/Oncology Goethe University Theodor-Stern-Kai 7 60590 Frankfurt Germany (1)
Department of Neuroscience, School of Medicine, University of Florida (1)
Department of Neurscience, College of Medicine, University of Florida (1)
ETH Zurich (1)
Epigenetics Program, Department of Biochemistry and Biophysics, Perelman School of Medicine, University of Pennsylvania (1)
European Molecular Biology Laboratory (1)
Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, United States (1)
Leibniz Institute on Aging – Fritz Lipmann Institute (FLI) Beutenbergstrasse 11 07745 Jena, Germany (1)
Lewis Seigler Institute of Interactive Genomics and Depatment of MOlecular Biology, Princeton University (1)
Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, NJ, USA Department of Molecular Biology, Princeton University, Princeton, NJ, USA (1)
Molecular Biology and Lewis-Sigler Institute for Intergrative Genomics, Princeton University, USA (1)
Neufeld and Tamman Cardiovascular Research Institutes, Sheba Medical Center, Sackler School of Medicine, Tel Aviv University, Israel. (1)
Professor of Pharmaceutical Sciences & Moulder Center for Drug Discovery Professor Lewis Katz School of Medicine Member Fox Chase Cancer Institute Director of Proteomics/Metabolomics Temple University School of Pharmacy (1)
Professor of Pharmaceutical Sciences & Moulder Center for Drug Discovery Professor Lewis Katz School of Medicine Member Fox Chase Cancer Institute Director of Proteomics/Metabolomics Temple University School of Pharmacy 3307 N Broad Street Room 552 Philadelphia, PA 19140 Tel: 215 707 9228 (1)
Structural Genomics Consortium (SGC), Chemical biology Group, University of Oxford, United Kingdom. also affiliated with: Target Discovery Institute, Nuffield Department of Medicine, University of Oxford, United Kingdom. (1)

IsPrivate

False (1)

Submitter Keywords

FROG (1)

Study type

Transcription profiling by array (54)
ChIP-seq (24)
RNA-seq of coding RNA (5)
Comparative genomic hybridization by array (3)
RNA-seq of non coding RNA (3)
Baseline (2)
Unknown experiment type (2)
Other (1)
Methylation profiling by array (1)
Proteomic profiling by array (1)
RNA-seq of coding RNA from single cells (1)
Methylation profiling by high throughput sequencing (1)

Release Date

2021 (461)
2022 (456)
2025 (451)
2024 (428)
2023 (427)
2020 (350)
2019 (288)
2018 (284)
2016 (194)
2017 (168)
2015 (155)
2014 (136)
2011 (107)
2013 (102)
2012 (89)
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2009 (56)
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2006 (16)
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2002 (3)
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2000 (2)

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Untargeted gas chromatography–mass spectrometry-based metabolomics analysis of kidney and liver tissue from the Lewis Polycystic Kidney rat

Polycystic kidney disease (PKD) encompasses a spectrum of inherited disorders that lead to end-stage renal disease (ESRD). There is no cure for PKD and current treatment options are limited to renal replacement therapy and transplantation. A better understanding of the pathobiology of PKD is needed ...

2023-01-26 | MTBLS748 | MetaboLights

NMR based metabolomics study of Y2 receptor activation by neuropeptide Y in the SK-N-BE2 human neuroblastoma cell line

Neuropeptide Y (NPY) and its Y2 receptors (Y2R) play an important role in regulating growth of various tumors and are highly expressed in human neuroblastoma brain tumors. Cell lines derived from neuroblastoma brain tumors provide a good model to study the consequences of NPY activation of Y2R in tu...

2014-10-01 | MTBLS104 | MetaboLights

Lewis lung carcinoma cells and TDAG8 overexpression

We observed the effects of TDAG8-overexpression in Lewis lung carcinoma (LLC) cells on the gene expression pattern. TDAG8-overexpressing or vector-transfected control LLC cells (5 × e5 in 200 µL of HBSS) were injected into the lateral tail veins of 6–8-week-old C57BL/6 mice. Lungs were removed on da...

ORGANISM(S): Mus musculus

2010-09-06 | E-GEOD-18244 | biostudies-arrayexpress

miRNA expression in myeloid-derived suppressor cells (MDSCs) treated with or without whole ?-glucan particles (WGP)

Murine MDSCs isolated from the spleens of Lewis lung carcinoma mice were treated with or without WGP, and then miRNA array was used to analyze the differentailly expressed miRNAs. Murine MDSCs were isolated from the spleens of Lewis lung carcinoma tumor-bearing mice, and the sorted MDSCs were stimul...

ORGANISM(S): Mus musculus

2015-06-26 | E-GEOD-67578 | biostudies-arrayexpress

Synthesis of Lewis Y Analogues and Their Protein Conjugates for Structure-Immunogenicity Relationship Studies of Lewis Y Antigen.

Not available

S-EPMC7203683 | biostudies-literature

Therapeutic targeting of Lewis(y) and Lewis(b) with a novel monoclonal antibody 692/29.

Not available

S-EPMC3568143 | biostudies-literature

Lewis y antigen promotes the proliferation of ovarian carcinoma-derived RMG-I cells through the PI3K/Akt signaling pathway.

Not available

S-EPMC2806302 | biostudies-literature

Expression of the Carbohydrate Lewis Antigen, Sialyl Lewis A, Sialyl Lewis X, Lewis X, and Lewis Y in the Placental Villi of Patients With Unexplained Miscarriages.

Not available

S-EPMC8202085 | biostudies-literature

A Novel Bispecific Antibody Targeting CD3 and Lewis Y with Potent Therapeutic Efficacy against Gastric Cancer.

Not available

S-EPMC8393954 | biostudies-literature

Cancer anorexia: the role of serotonin in hypothalamic resistance of the neuropeptide Y system [A286_GEO_LLM]

Anorexia is a common symptom among cancer patients and contributes to malnutrition and insufficient food intake. In cancer-induced anorexia, food intake regulation in the hypothalamus appears to be impaired. A negative energy balance persists and accelerates muscle wasting and malnutrition. Moreove...

ORGANISM(S): Mus musculus

2014-10-31 | E-GEOD-57188 | biostudies-arrayexpress

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