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MetabolomicsTowards engineering ectomycorrhization into switchgrass bioenergy crops via a lectin receptor-like kinase
Soil-borne microbes can establish compatible relationships with host plants, providing a large variety of nutritive and protective compounds in exchange for photosynthesized sugars. However, the molecular mechanisms mediating the establishment of these beneficial relationships remain unclear. Our pr...
2021-08-11 | MTBLS2597 | MetaboLights
UnknownEffects of polymorphisms in pepsinogen (PEP), amylase (AMY) and trypsin (TRY) genes on food habit domestication traits in mandarin fish.
Not available
S-EPMC3856018 | biostudies-literature
TranscriptomicsCircadian patterns of gene expression in the human brain and disruption in major depressive disorder
A cardinal symptom of Major Depressive Disorder (MDD) is the disruption of circadian patterns. Yet, to date, there is no direct evidence of circadian clock dysregulation in the brains of MDD patients. Circadian rhythmicity of gene expression has been observed in animals and peripheral human tissues,...
ORGANISM(S): Homo sapiens 
2013-04-20 | E-GEOD-45642 | biostudies-arrayexpress
UnknownFirst echinoderm alpha-amylase from a tropical sea cucumber (Holothuria leucospilota): Molecular cloning, tissue distribution, cellular localization and functional production in a heterogenous E.coli system with codon optimization.
Not available
S-EPMC7491741 | biostudies-literature
GenomicsWhole Genome Association Study of Bipolar Disorder

The goal of the project is to identify genes that make individuals more susceptible to bipolar disorder (manic depressive illness) and to better understand the brain pathways involved in the disease.

Dataset versioning

  • Version 1: European-American (EA) ancestr...
phs000017.v3.p1 | EGA
TranscriptomicsRNA-sequencing of the mRNA transcriptome in lesional and non-lesional skin, across three time-points in severe psoriasis patients treated with the tumor necrosis factor (TNF) inhibitor, etanercept
Blood (mRNA and miRNA) and skin mRNA transcriptomes were investigated across three time-points in a pilot investigation of ten severe psoriasis patients, treated with the tumor necrosis factor (TNF) inhibitor, etanercept. We used illumina RNA-sequencing to analyse the small-RNA transcriptome in bloo...
ORGANISM(S): Homo sapiens 
2018-09-21 | E-MTAB-6556 | biostudies-arrayexpress
UnknownFish oil supplementation alters emotion-generated corticolimbic functional connectivity in depressed adolescents at high-risk for bipolar I disorder: A 12-week placebo-controlled fMRI trial.
Not available
S-EPMC8720319 | biostudies-literature
ProteomicsCocaine-Induced Restructuring of the Rat Brain Peptidome: Quantitative Mass Spectrometry Reveals Anatomically Specific Patterns of Cocaine-Regulated Peptide Expression
Substance abuse, particularly cocaine, has detrimental effects on global public health, as acute intoxication often results in adverse outcomes and current pharmacological treatments exhibit limited effectiveness. The intricate process of cocaine intoxication involves substantial alterations in the ...
ORGANISM(S): Rattus norvegicus (Rat) 
2025-01-02 | PXD042363 | Pride
Rat Brain Peptidome Lc-ms/ms 
UnknownGut microbiota-related metabolite alpha-linolenic acid mitigates intestinal inflammation induced by oral infection with Toxoplasma gondii.
Not available
S-EPMC10714487 | biostudies-literature
TranscriptomicsNLRC5 is a transcriptional regulator of MHC class I genes
NLRC5 is a member of the NLR family of proteins. The observation that NLRC5 is found in the nucleus prompted us to perform a gene array to identify putative target genes of NLRC5. We generated Jurkat T cell lines that stably express either the wild-type or mutant forms of NLRC5 harboring mutations i...
ORGANISM(S): Homo sapiens 
2010-07-30 | E-GEOD-22064 | biostudies-arrayexpress
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