Sort   by:  
 Page size 
TranscriptomicsExpression data from mouse tissue Angiotensin II treated for 0,1,3,7days
Angiotensin II (Ang II) mediated signaling plays a key role in the development of hypertension associated target organ damages. However, the gene expression changes regulated by Ang II in the early stage of acute cerebral, cardiac, renal, vascular injury remain unclear. we investigated Ang IIâ??medi...
ORGANISM(S): Mus musculus 
2014-07-16 | E-GEOD-59437 | biostudies-arrayexpress
TranscriptomicsmiRNAs expression profiling from mouse heart after Ang II (angiotensin II) (1500ng/kg/min) infusion for 3 days and 7 days
Angiotensin II stimulates fibroblast proliferation and substantially alters gene expression patterns leading to cardiac remodeling, but the mechanisms for such differences are unknown. MicroRNAs are a novel mechanism for gene expression regulation. Herein we tested the miRNAs patterns in mouse heart...
ORGANISM(S): Mus musculus 
2015-06-05 | E-GEOD-69559 | biostudies-arrayexpress
ProteomicsTime-series proteome profiling analysis of the atria in a murine model of angiotensin II-induced atrial fibrillation
Atrial fibrillation (AF) is the most common form of arrhythmia observed in clinical cardiac diseases. Angiotensin II (Ang II) and elevation of blood pressure have been considered to be the main risk regulators of AF. However, the time series proteome profiling and the key signaling pathways involved...
ORGANISM(S): Mus musculus (Mouse) 
2022-04-04 | PXD022238 | Pride
Proteomics  time series protein expression profiling  angiotensin ii  atrial fibrillation 
UnknownTherapeutic Delivery of Ang(1-7) via Genetically Modified Probiotic: A Dosing Study.
Not available
S-EPMC7109904 | biostudies-literature
TranscriptomicsMitochondrial functional aberrations in a mouse model of non-ischemic heart failure
We characterized the metabolic and cardiac mitochondrial function in a mouse model of non-ischemic HF. Inhibition of nitric oxide synthesis and hypertension, which often present together, are two important risk factors in human non-ischemic HF. Compared with L-NAME L-NG-Nitroarginine methyl ester (L...
ORGANISM(S): Mus musculus 
2016-01-19 | E-GEOD-72132 | biostudies-arrayexpress
ProteomicsEndothelial OTUD1 promotes Ang II-induced vascular remodeling by deubiquitinating SMAD3
Understanding the molecular mechanisms of pathological vascular remodeling is important for treating cardiovascular diseases and complications. Recent studies have highlighted a role of deubiquitinases in vascular pathophysiology. In this study, we investigated the role of a deubiquitinase, OTUD1, i...
ORGANISM(S): Homo sapiens (Human) 
2022-12-24 | PXD037926 | Pride
Huvec  lc-ms/ms 
UnknownEvidence for a Physiological Mitochondrial Angiotensin II System in the Kidney Proximal Tubules: Novel Roles of Mitochondrial Ang II/AT1a/O2- and Ang II/AT2/NO Signaling.
Not available
S-EPMC7299167 | biostudies-literature
UnknownOral delivery of ACE2/Ang-(1-7) bioencapsulated in plant cells protects against experimental uveitis and autoimmune uveoretinitis.
Not available
S-EPMC4429699 | biostudies-literature
UnknownTargeting GPR39 in structure-based drug discovery reduces Ang II-induced hypertension.
Not available
S-EPMC11538459 | biostudies-literature
UnknownMyeloid ACE2 protects against septic hypotension and vascular dysfunction through Ang-(1-7)-Mas-mediated macrophage polarization.
Not available
S-EPMC10788636 | biostudies-literature
Sort   by:  
 Page size