Huvec - OmicsDI

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Unknown (1486)
Genomics (737)
Transcriptomics (646)
Proteomics (115)
Other (11)
Metabolomics (8)
Methylation profiling (7)

Organisms

Homo sapiens (747)
Bombyx mori (93)
Klebsiella pneumoniae (93)
Schizosaccharomyces pombe (93)
Streptomyces coelicolor A3(2) (93)
Human immunodeficiency virus 1 (93)
Oryza sativa Indica Group (93)
Sinorhizobium meliloti BL225C (93)
Mus musculus (20)
Rattus norvegicus (8)
Danio rerio (4)
synthetic construct (3)
Human gammaherpesvirus 8 (3)
Caenorhabditis elegans (3)
Drosophila melanogaster (3)
Candida albicans (2)
JC polyomavirus (2)
Betapolyomavirus hominis (2)
Betapolyomavirus macacae (2)
human gammaherpesvirus 4 (2)
Human alphaherpesvirus 1 (2)
Murid betaherpesvirus 1 (2)
Murid gammaherpesvirus 4 (2)
Human betaherpesvirus 5 (2)
Human immunodeficiency virus 1 (2)
Human herpesvirus 8 strain rKSHV.219 (1)
Human herpesvirus 8 type M (1)
Porphyromonas gingivalis ATCC 33277 (1)
Rubivirus rubellae (1)
Staphylococcus aureus (1)

Organisms

Homo sapiens (565)
Mus musculus (6)
Human gammaherpesvirus 8 (1)
Mus musculus musculus (1)

Repository

ENA (643)
biostudies-arrayexpress (401)
geo (349)
pride (93)
MassIVE (10)
MetaboLights (8)
ExpressionAtlas (6)
iProX (5)
jPOST (5)
NODE (5)

Tissue

Cell culture (33)
Endothelial cell of umbilical vein (30)
HUVEC cell (13)
Umbilical vein (10)
Primary cell (7)
Endothelial cell (5)
N/a (4)
Permanent cell line cell (3)
Epithelial cell (3)
Pericyte cell (2)
Smooth muscle cell (2)
Endothelium (2)
Pluripotent stem cell (2)
Embryonic fibroblast (2)
Astrocyte (2)
Microvascular endothelial cell (2)
Blood plasma (2)
Stem cell (2)
HUVECs (1)
Regulation of endothelial cell differentiation (1)
Monocytic leukemia cell line (1)
Venous endothelial cell (1)
Lymphatic endothelial cell (1)
Blood vessel endothelium (1)
Embryonic blood vessel endothelial progenitor cell (1)
Mesenchymal stem cell of umbilical cord (1)
Endothelial cell of vascular tree (1)
Umbilical vein endothelial cell line (1)
Lung cancer cell line (1)
Blood vessel endothelial cell (1)

Disease

Cardiovascular system disease (3)
Disease free (3)
Breast cancer (2)
Advanced atherosclerosis (1)
AIDS-KS, HIV+, nodular (late) stage (1)
Non-diseased (1)
Arteriosclerotic cardiovascular disease (1)
Severe acute respiratory syndrome (1)
Atherosclerosis (1)
Chronic kidney disease (1)
Myocardial ischemia (1)
Liver cancer (1)

Technology Type

Mass Spectrometry (93)
Shotgun proteomics (61)
Bottom-up proteomics (16)
Data-dependent acquisition (9)
Affinity purification coupled with mass spectrometry proteomics (6)
Gel-based experiment (5)
Mass spectrometry (4)
Mass spectrometry assay (4)
SWATH MS (4)
Top-down proteomics (4)
Data-independent acquisition (3)
SRM/MRM (2)
All-ion fragmentation (1)
DiaPASEF (1)
HDMSE (1)

Instrument Platform

NextSeq 500 (7)
Illumina NovaSeq 6000 (5)
Q Exactive (5)
Illumina HiSeq 2500 (4)
Illumina HiSeq 2000 (4)
Agilent Microarray Scanner G2505C (2)
Agilent Hybridisation Oven G2545A (2)
HiSeq X Ten (2)
NextSeq 550 (2)
PC (1)
None (1)
Affymetrix GeneChip Scanner 3000 7G (1)
GenePix 4000A [Axon Instruments] (1)
BAS-5000 [FUJIFILM] (1)
DNA Microarray Scanner BA [Agilent Technologies] (1)
Illumina Genome Analyzer II (1)
NA (1)
NextSeq 2000 (1)
BGISEQ-500 (1)
Illumina HiSeq 3000 (1)
Illumina HiSeq 4000 (1)
LTQ FT (1)
Q Exactive HF-X (1)
Orbitrap Fusion (1)
Orbitrap Eclipse (1)
Q Exactive Plus (1)
Liquid Chromatography MS - alternating - HILIC (1)
Agilent 5975T LTM GC/MSD (Agilent) (1)
Gas Chromatography MS - Positive (GC-MS (Positive)) (1)
Liquid Chromatography MS - negative (1)

Publication Date

2013 (75)
2014 (62)
2012 (60)
2011 (60)
2010 (57)
2016 (54)
2022 (48)
2024 (45)
2015 (42)
2025 (41)
2009 (38)
2023 (37)
2019 (36)
2026 (33)
2021 (30)
2017 (30)
2020 (28)
2008 (26)
2018 (23)
2007 (18)
2005 (12)
2006 (8)
2004 (6)
2003 (4)

CHEBI ID

CHEBI:16015 (2)
CHEBI:144347 (1)
CHEBI:144346 (1)
CHEBI:144345 (1)
CHEBI:144344 (1)
CHEBI:144342 (1)
CHEBI:144322 (1)
CHEBI:144341 (1)
CHEBI:144340 (1)
CHEBI:144338 (1)
CHEBI:23623 (1)
CHEBI:144337 (1)
CHEBI:144336 (1)
CHEBI:144335 (1)
CHEBI:144333 (1)
CHEBI:144332 (1)
CHEBI:144331 (1)
CHEBI:144329 (1)
CHEBI:144320 (1)
CHEBI:144328 (1)
CHEBI:144327 (1)
CHEBI:144326 (1)
CHEBI:144325 (1)
CHEBI:144324 (1)
CHEBI:75892 (1)
CHEBI:46995 (1)
CHEBI:144343 (1)
CHEBI:41094 (1)
CHEBI:144334 (1)
CHEBI:67258 (1)

Metabolite Name

C00049 (1)
Tromethamine, 3TMS derivative (1)
Trimethylsilylpropargyl alcohol, 2TMS derivative (1)
Succinic acid, 2,2,3,3,4,4,5,5-octafluoropentyl 2-methylpent-3-yl ester (1)
Serine, 3TMS derivative (1)
Pyroglutamic acid, TMS derivative (1)
Propanoic acid, 3-[(tert-butyldimethylsilyl)oxy]-2-methyl-, tert-butyldimethylsilyl ester (1)
Propanedioic acid, 2TBDMS derivative (1)
Phthalic acid, di(3-methylphenyl) ester (1)
Phosphorylethanolamine, 4TMS derivative (1)
Phosphoric acid, bis[2,3-bis[(trimethylsilyl)oxy]propyl] trimethylsilyl ester (1)
Phosphonic acid, (aminomethyl)-, bis(trimethylsilyl) ester (1)
Phenylethyl Alcohol, TMS derivative (1)
Phenylalanine, 2TMS derivative (1)
Octanoic acid, tributylsilyl ester (1)
N-Acetyl-L-glutamic acid, 2TMS derivative (1)
N-.alpha.-Acetyl-L-Lysine, 3TMS derivative (1)
Myrtenoic acid, trimethylsilyl ester (1)
Monolaurin, 2TMS derivative (1)
Methyltris(trimethylsiloxy)silane (1)
Methylsuccinic acid, 2TMS derivative (1)
Mercaptoacetic acid, 2TMS derivative (1)
Malonic acid, bis(2-trimethylsilylethyl ester (1)
Lysine, 3TMS derivative (1)
L-Valine, TMS derivative (1)
L-Threonine, 3TMS derivative (1)
L-Serine, 2TMS derivative (1)
L-Proline, TMS derivative (1)
L-Proline, n-propargyloxycarbonyl-, propargyl ester (1)
L-Proline, 2TMS derivative (1)

First Public Date

2014 (153)
2024 (83)
2023 (54)
2020 (51)
2022 (44)
2026 (43)
2021 (38)
2019 (38)
2025 (36)
2018 (35)
2017 (25)
2015 (17)
2016 (16)
2013 (10)

Classification

viruses (1)

Modification

57.021464 (2)
31.989829 (1)
79.966331 (1)
-17.026549 (1)
42.010565 (1)
15.994915 (1)

Study type

Transcription profiling by array (262)
RNA-seq of coding RNA (45)
ChIP-seq (39)
Unknown experiment type (12)
Other (7)
Transcription profiling by RT-PCR (4)
Methylation profiling by array (4)
Cell line - High-throughput sequencing (3)
MicroRNA profiling by array (3)
RNA-seq of non coding RNA (3)
Human - High-throughput sequencing (2)
Transcription profiling by tiling array (2)
RNAi profiling by array (2)
DNA-seq (2)
RNA-seq of total RNA (2)
ChIP-chip by tiling array (1)
Cell line - One-color microarray (1)
ChIP-chip by array (1)
MicroRNA profiling by high throughput sequencing (1)
Comparative genomic hybridization by array (1)
Proteomic profiling by array (1)
CUT&RUN (1)
Methylation profiling by high throughput sequencing (1)

Release Date

2022 (176)
2021 (175)
2023 (148)
2020 (144)
2025 (138)
2024 (111)
2019 (98)
2018 (98)
2016 (96)
2014 (94)
2013 (93)
2017 (88)
2015 (81)
2012 (80)
2010 (67)
2011 (61)
2009 (43)
2008 (30)
2026 (17)
2007 (17)
2005 (14)
2006 (5)
2004 (4)
2003 (3)
2002 (2)
2001 (2)
2000 (1)
1999 (1)

Lab affiliation

University of Vienna, Faculty of Chemistry, Department of Analytical Chemistry (9)
Leibniz Institute on Aging – Fritz Lipmann Institute (FLI), 07745 Jena, Germany (4)
Institute for Vascular Signalling, Centre for Molecular Medicine, Goethe University, Frankfurt am Main, Germany. (3)
Institut für Kardiovaskuläre Physiologie, Goethe-Universität, Frankfurt am Main, Germany (2)
Institute for Vascular Signalling, Centre for Molecular Medicine, Goethe University, Frankfurt am Main, Germany (2)
Cardiovascular Division, King's College London (2)
Department of Molecular Physiology and Biological Physics, University of Virginia, Charlottesville, VA USA (2)
Medical University of Vienna (2)
Amsterdam UMC, Vrije Universiteit Amsterdam, Medical Oncology, Cancer Center Amsterdam, OncoProteomics Laboratory, Amsterdam, Netherlands (2)
State University of Rio de Janeiro (1)
Centre of Excellence in New Target Discovery (CENTD), Butantan Institute, Sao Paulo, Brazil. (1)
Institute Krems Bioanalytics, IMC University of Applied Sciences Krems, 3500 Krems, Austria (1)
University of Eastern Piedmont Department of Sciences and Technological Innovation, University of Piemonte Orientale, Italy (1)
Forschungsinstitut für Frauengesundheit Universitäts- Frauenklinik Universitätsklinikum Tübingen Germany (1)
Centre for Genomics and Computational Biology Barts Cancer Institute Queen Mary, University of London John Vane Science Centre, Charterhouse Square, London EC1M 6BQ (1)
Max-Delbrück Center for molecular medicine Robert-Rössle Strasse 10 13125 Berlin (1)
Angiogenesis & Metabolism Laboratory, Max Planck Institut for Heart and Lung Research, 61231 Bad Nauheim, Germany (1)
Laboratory of regenerative biomedicine, Institute of cytology of the Russian Academy of Science (1)
Associate Professor, Department of biotechnology and research, Sir Ganga ram hospital, New Delhi -110060, Delhi, India (1)
Department of Pediatric Cardiology and Critical Care; Pulmonary Vascular Research Center; Hannover Medical School; Hannover; Germany (1)
733 N. Broadway Miller Research Building room 527 Johns Hopkins University Baltimore, MD 21205 (1)
Senior Scientist, RI-MUHC , Glen site Child Health and Human Development Program Centre for Translational Biology Professor, Department of Pediatrics, Faculty of Medicine and Health Sciences, McGill University Department of Pediatrics, Division of Hematology, MUHC (1)
Additional Professor and Head Department of Biotechnology, Ail India institute of Medical Sciences New Delhi -110029 (1)
Institute for Microbiology and Infection, School of Biosciences, University of Birmingham, Birmingham B15 2TT UK (1)
MD,PhD Professor Harvard Medical School (1)
Division of Cardiovascular Medicine, Department of Medicine, Abboud Cardiovascular Research Center, University of Iowa Carver College of Medicine, Iowa City, Iowa, USA. Fraternal Order of Eagles Diabetes Research Center, Pappajohn Biomedical Institute, and Heart and Vascular Center, University of Iowa, University of Iowa, Iowa City, Iowa, USA. (1)
Department of Chemistry and Biochemistry, Texas Tech University, Lubbock, TX (1)
Department of Molecular Physiology and Biological Physics University of Virginia School of Medicine Charlottesville, VA, USA 22908 (1)
Cancer Research UK Manchester Institute, The University of Manchester, Wilmslow Road, Manchester M20 4BX, United Kingdom (1)
Key Laboratory of Medical Molecular Virology (MOE/NHC/CAMS), School of Basic Medical Sciences, Shanghai Medical College, Fudan University, Shanghai, China. (1)

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Stable isotope resolved analysis of HUVEC Cells under normaxia and hypoxia

In order to analyze HUVECs under normoxia and hypoxia, cells were initially deprived of excess nutrients and hormones by maintaining them overnight in a restricted medium with only 2% fetal bovine serum, and incubated for 40 hours in the presence of the tracer [1,2-13C2]-glucose until sample collect...

2017-12-18 | MTBLS412 | MetaboLights

Integrated Proteomics and Metabolomics Analysis Reveals Differential Lipid Metabolism in HUVEC under high and low shear stress

OBJECTIVE: Atherosclerotic plaque development is closely associated with the hemodynamic forces applied to endothelial cells (EC). Among these, shear stress (SS) plays a key role in disease development since changes in flow intensity and direction could stimulate an atheroprone or athero...

2019-07-25 | MTBLS739 | MetaboLights

Transcription profiling by array of human umbilical vein endothelial cells (HUVEC) stimulated with TNF vs. controls reveals TNF induces distinct expression programs

HUVEC were left untreated or stimulated for 5h with 2 ng/ml TNF. Comparsion of the gene profiles revealed TNF-mediated gene expression changes in HUVEC.

ORGANISM(S): Homo sapiens

2007-11-01 | E-GEOD-2639 | biostudies-arrayexpress

Expression profiling in Human Umbilical Vein Endothelial Cells (HUVEC)

Whole transcriptome gene expression profiling of Normal -(HUVEC) Human Umbilical Vein Endothelial Cells The HUVEC gene expression results analyzed in this study are further described in Kustermann S. et al. (2014) A real-time impedance based screening assay for drug induced vascular leakage. A Nimbl...

ORGANISM(S): Homo sapiens

2014-01-07 | E-GEOD-52044 | biostudies-arrayexpress

Transcription profiling of human tumor-conditioned versus quiescent HUVEC cells, and 5-aza-2a??-deoxycytidine and trichostatin AI treated cells to identify epigenetically silenced genes

Tumor angiogenesis requires intricate regulation of gene expression in endothelial cells (EC). We recently showed that DNA methyltransferase (DNMT)- and histone deacetylase (HDAC) inhibitors directly repress EC growth and tumor angiogenesis, suggesting that epigenetic modifications mediated by DNMTs...

ORGANISM(S): Homo sapiens

2008-06-15 | E-GEOD-7132 | biostudies-arrayexpress

Expression data from HUVEC with YAP siRNA knockdown

YAP knockdown in HUVEC elicits proliferation and cell cycle preogression defects. YAP deficient cells caused arrest in G1 and defects in S-phase entry. The microarray analysis was conducted to identify potential YAP targets that are involved in HUVEC cell cycle regulation mRNA samples were collected...

ORGANISM(S): Homo sapiens

2014-10-17 | E-GEOD-61989 | biostudies-arrayexpress

Gene expression profiling of caffeic acid phenethyl ester-treated human umbilical vein endothelial cells-1

Caffeic acid phenethyl ester (CAPE), derived from various plant sources, has been shown to ameliorate ischemia/reperfusion (I/R) injury in vivo, and this has been attributed to its ability to reduce the oxidative stress. Here we investigated the cytoprotection of CAPE against menadione (MD)-induced ...

ORGANISM(S): Homo sapiens

2010-05-26 | E-GEOD-10413 | biostudies-arrayexpress

Homo sapiens strain:HUVEC

Effects of ABTAA on HUVEC

PRJNA309624 | ENA

Gene expression profiling of caffeic acid phenethyl ester-treated human umbilical vein endothelial cells-2

ORGANISM(S): Homo sapiens

2010-05-26 | E-GEOD-10429 | biostudies-arrayexpress

mRNA expression after siRNA-mediated knock down of Enhancer of zeste homolog 2 (Ezh2) in human umbilical vein endothelial cells

mRNA expression after Ezh2 knock down was analyzed to identify genes regulated by Ezh2. Human umbilical vein endothelial cells (HUVEC) were transfected with 25 nmol/L of control small interfering RNA (siRNA) (Silencer Select Negative Control Ambion, Austin, TX) or siRNA directed against Ezh2 (s4918;...

ORGANISM(S): Homo sapiens

2012-10-16 | E-GEOD-41610 | biostudies-arrayexpress

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