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ProteomicsA proteomic view of WT and △ydiV(stm1344) Salmonella Typhimurium in simulated host environment medium
The flagellum provides essential motility in the pathogenic process of Salmonella host invasion. However, flagellin is strongly antigenic and can be recognized by TLR5, resulting in activation of the host immune system to clear the invading pathogen. The presence of flagella also disrupts the integr...
ORGANISM(S): Escherichia coli 
2022-10-12 | PXD035693 | Pride
Differential protein expression  simulated host environment medium  wt and △ydiv 
ProteomicsIdentification of cellular proteins interacting with PEDV M protein through APEX2 labeling
Membrane (M) proteins of coronaviruses are the most abundant component of the virus envelope and play crucial roles in virus assembly, virus budding and the regulation of host immunity. To understand more about these functions in the context of PEDV M protein, forty host cell proteins interacting wi...
ORGANISM(S): Sus Scrofa Scrofa 
2021-03-07 | PXD024559 |
MetabolomicsArginine depletion-induced autophagy and metabolic dysregulation are involved in the disease severity of hand, foot, and mouth disease
Amino acid metabolism provides significant insight into the development and prevention of many viral diseases. Therefore, the present study aimed to compare the amino acid profiles of hand, foot, and mouth disease (HFMD) patients with those of healthy individuals and to further reveal the molecular ...
2024-10-25 | MTBLS11341 | MetaboLights
ProteomicsIdentification of SNHG9-binding proteins in Huh7 cells using RNA pull-down assay
This project aims to identify the specific proteins interacting with lncRNA SNHG9 in hepatoma cells. We performed RNA pull-down assays using biotin-labeled SNHG9 probes in Huh7 cell lysates, followed by mass spectrometry (LC-MS/MS) to analyze the pulled-down protein.
ORGANISM(S): Homo Sapiens 
2026-04-20 | PXD077375 |
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