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MetabolomicsMetabolomic approaches to dissect dysregulated metabolism in the progression of pre-diabetes to T2DM

Most of pre-diabetes were eventually progress to diabetes, thereby profiling of prediabetic metabolic disorders may be an effective targeted preventive measure. We aimed to elucidate internal motivation of the progression of pre-diabetes to type 2 diabetes mellitus (T2DM) from a metabolic perspec...

2024-04-29 | MTBLS8644 | MetaboLights
UnknownFive New Cucurbitane-Type Triterpenoid Glycosides from the Rhizomes of Hemsleya penxianensis with Cytotoxic Activities.
Not available
S-EPMC6720345 | biostudies-literature
TranscriptomicsTranscription profiling of rat epididymal fat tissues from diet induced obesity model against lean controls
Analysis of gene expression profiles of epididymal fat from DIO rats; We applied a comparative functional genomics approach to evaluate diet-induced obese (DIO) rats as an obesity model Experiment Overall Design: Gene expression profiles from DIO and lean rats were generated and compared. A private ...
ORGANISM(S): Rattus norvegicus 
2009-04-23 | E-GEOD-8700 | biostudies-arrayexpress
UnknownResidual breast cancers after conventional therapy display mesenchymal as well as tumor-initiating features.
Not available
S-EPMC2720409 | biostudies-literature
UnknownThe Chromosome-Level Genome of Hestina assimilis (Lepidoptera: Nymphalidae) Reveals the Evolution of Saprophagy-Related Genes in Brush-Footed Butterflies.
Not available
S-EPMC9917059 | biostudies-literature
TranscriptomicsmiR in wound healing
MicroRNA microarray profiling analysis was performed on skin biopsies from unwounded mice, and from mice 1 day or 5 days post-wounding (3 mice per groups)
ORGANISM(S): Mus musculus 
2013-02-28 | E-MTAB-1518 | biostudies-arrayexpress
TranscriptomicsPancreatic islet expression profiling in diabetes prone C57BLKS/J mice vs C57BL6/J mice.
C57BLKS/J mice are susceptible to diabetes, because of islet dysfunction, whereas C57BL6/J mice are not. Differences in gene expression between the two strains may account for this sensitivity. Furthermore these differences may only be evident in the hyperstimulated (diabetic or hyperglycemic) state...
ORGANISM(S): Mus musculus 
2008-12-30 | E-GEOD-11257 | biostudies-arrayexpress
GenomicsThe response regulator ArcA uses a diverse binding site architechture to globally regulate carbon oxidation in E. coli [ChIP-Seq]
We found many binding sites for ArcA under glucose fermentative anaerobic growth conditions. Descirbed in the manuscript "The response regulator ArcA uses a diverse binding site architechture to globally regulate carbon oxidation in E. coli" Examination of occupancy of ArcA under anaerobi...
ORGANISM(S): Escherichia coli str. K-12 substr. MG1655 
2013-10-17 | E-GEOD-46414 | biostudies-arrayexpress
TranscriptomicsAI-2-dependent gene regulation in Staphylococcus epidermidis
Autoinducer 2 (AI-2), a widespread by-product of the LuxS-catalyzed S-ribosylhomocysteine cleavage reaction in the activated methyl cycle, has been suggested to serve as an intra- and interspecies signaling molecule, but in many bacteria AI-2 control of gene expression is not completely understood. ...
ORGANISM(S): Staphylococcus epidermidis 
2008-10-10 | E-GEOD-9427 | biostudies-arrayexpress
MetabolomicsMetabolomics Study of Serum and Urine Samples Reveals Metabolic Pathways and Biomarkers Associated with Pelvic Organ Prolapse
Pelvic organ prolapse (POP) is a common medical condition among women and involves complicated diagnostics and controversial surgical management. The exact molecular mechanism underlying POP is poorly understood, especially at the metabolism level. To explore the metabolic mechanism underlying POP a...
2019-08-14 | MTBLS1033 | MetaboLights
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