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TranscriptomicsExpression data from different photosynthetic rate in Populus.
Despite the significance of nucleus genes in plant growth and development, little is known of the molecular bases of regulation of photosynthesis in woody plants.Hence discovering the genetic basis for photosynthesis related phenotypic variation and identifying the major genes controlling these comp...
ORGANISM(S): (Populus alba x Populus glandulosa) x Populus tomentosa 
2014-05-31 | E-GEOD-47105 | biostudies-arrayexpress
TranscriptomicsRole of de novo DNA methyltransferases in hematopoietic stem cells (RNA-seq)
To investigate the global transcriptome expression in Dnmt3ab dKO HSCs, we performed high-throughput sequencing of Poly A+ RNA (RNA-Seq) from purified HSCs (SP-KSL-CD150+). With biological duplicates, more than 200 million reads in total for each genotype of HSC were obtained. Mouse hematopoietic st...
ORGANISM(S): Mus musculus 
2014-08-19 | E-GEOD-50775 | biostudies-arrayexpress
GenomicsEpigenetic and genetic changes during mouse hematopoietic stem cell aging [Bisulfite-Seq]
To investigate the global DNA methylation changes in mouse hematopoietic stem cell aging, we performed whole-genome bisulfite sequencing (WGBS). We generated 1,494 million (4mo HSCs), and 1,493 million (24mo HSCs) raw reads; about 82.6% and 84.3%, respectively, were successfully aligned to either st...
ORGANISM(S): Mus musculus 
2014-04-30 | E-GEOD-47815 | biostudies-arrayexpress
GenomicsRole of de novo DNA methyltransferases in hematopoietic stem cells (WGBS)
To investigate the global DNA methylation changes in Dnmt3a-KO and Dnmt3ab-dKO HSCs compared to control HSCs, we performed whole genome bisulfite sequencing Mouse hematopoietic stem cell DNA methylation profiles of control, Dnmt3a-KO and Dnmt3ab-dKO HSCs were generated generated by deep sequencing,...
ORGANISM(S): Mus musculus 
2014-08-19 | E-GEOD-50780 | biostudies-arrayexpress
TranscriptomicsRole of de novo DNA methyltransferases in hematopoietic stem cells
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Mus musculus 
2014-08-19 | E-GEOD-50793 | biostudies-arrayexpress
Genomicsde novo DNA Methylation Balances Hematopoietic Stem Cell Self-Renewal and Differentiation
Cytosine methylation is an epigenetic mark usually associated with gene repression. Despite a requirement for de novo DNA methylation for differentiation of embryonic stem cells, its role in somatic stem cells is unknown. Using conditional ablation, we show that loss of either, or both, Dnmt3a or Dn...
ORGANISM(S): Mus musculus 
2011-09-30 | E-GEOD-27322 | biostudies-arrayexpress
ProteomicsMolecular Landscape of Atherosclerotic Plaque Progression: Insights from Proteomics
This dataset comprises proteomic profiles of 87 human carotid atherosclerotic plaques from patients undergoing carotid endarterectomy (CEA). The study employed an integrated approach using Data Independent Acquisition (DIA) proteomics. A total of 87 human carotid plaques were analyzed to identify an...
ORGANISM(S): Homo Sapiens 
2025-03-26 | PXD062283 |
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