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TranscriptomicsTranscription profiling of skin from wild type and Hoxc13 transgenic mice to investigate their propensity to develop severe hair growth defects and alopecia
A study of the effects of Hoxc13 overexpression in skin using Hoxc13 transgenic mice (GC13) known to develop severe hair growth defects and alopecia. Total skin from GC13 mice 5 dpn is compared to total skin from normal FVB mice 5 dpn using Affymetrix HG-U74Av2 GeneChips.
ORGANISM(S): Mus musculus 
2007-12-04 | E-GEOD-2374 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse leukemia initiation cells of SALL4B transgenic strains and their control counterparts
To compare the gene expression profiles of leukemia initiation cells of SALL4B transgenic mice and their control counterparts.
ORGANISM(S): Mus musculus 
2009-10-20 | E-MEXP-2072 | biostudies-arrayexpress
TranscriptomicsExpression data from RUNX1(41-214)-expressing and Runx1-knockout mice KSL cells
Mutations of RUNX1 are detected in patients with myelodysplastic syndrome (MDS). In particular, C-terminal truncation mutations lack a transcription regulatory domain and have increased DNA binding through the runt homology domain (RHD). The expression of the RHD, RUNX1(41-214), in mouse hematopoiet...
ORGANISM(S): Mus musculus 
2012-11-29 | E-GEOD-40155 | biostudies-arrayexpress
ProteomicsThe N-cadherin interactome in primary cardiomyocytes as defined by quantitative proximity proteomics
Low levels of Cdh2-BioID2 were expressed in mouse primary neonatal cardiomyocytes using an adenoviral expression system. Infected cells were treated with biotin for 24 hours before lysis. Biotinylated proteins were precipitated from lysates using streptavidin beads. Protein samples were in-gel tryps...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2019-01-24 | MSV000083362 | MassIVE
GenomicsLoss of PHF20 does not negatively affect deposition of H4K16 acetylation, but does impact the expression of MOF targets
Protein post-translational modifications transmit signals in part by creating binding sites for effector molecules. This is especially true in epigenetic pathways where histone tails are heavily modified, resulting in the recruitment of molecules that can affect transcription. One such molecule, pla...
ORGANISM(S): Mus musculus 
2012-02-27 | E-GEOD-29306 | biostudies-arrayexpress
OtherThe N-cadherin interactome in primary cardiomyocytes
Low levels of Cdh2-BioID2 were expressed in mouse primary neonatal cardiomyocytes using an adenoviral expression system. Infected cells were treated with biotin for 24 hours before lysis. Biotinylated proteins were precipitated from lysates using streptavidin beads. Protein samples were in-gel tryps...
ORGANISM(S): Mus Musculus 
2019-01-23 | MSV000083356 | MassIVE
UnknownHLA-haploidentical TCRαβ+/CD19+-depleted stem cell transplantation in children and young adults with Fanconi anemia.
Not available
S-EPMC7948273 | biostudies-literature
UnknownDesign, synthesis and biological evaluation of 3,5-disubstituted 2-amino thiophene derivatives as a novel class of antitumor agents.
Not available
S-EPMC4170804 | biostudies-literature
TranscriptomicsPorcine gene response following incision with energized devices
This study compares the gene expression changes in Sus scrofa in response to two different methods for abdominal surgical incisions ; electrosurgery and harmonic blade. As the use of laparoscopic surgery has become more widespread in recent years, the need has increased for minimally-invasive surgic...
ORGANISM(S): Sus scrofa 
2013-12-15 | E-GEOD-47710 | biostudies-arrayexpress
UnknownDiscovery and optimization of a series of 2-aryl-4-amino-5-(3',4',5'-trimethoxybenzoyl)thiazoles as novel anticancer agents.
Not available
S-EPMC3390948 | biostudies-literature
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