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ProteomicsA proteomic view of WT and △ydiV(stm1344) Salmonella Typhimurium in simulated host environment medium
The flagellum provides essential motility in the pathogenic process of Salmonella host invasion. However, flagellin is strongly antigenic and can be recognized by TLR5, resulting in activation of the host immune system to clear the invading pathogen. The presence of flagella also disrupts the integr...
ORGANISM(S): Escherichia coli 
2022-10-12 | PXD035693 | Pride
Differential protein expression  simulated host environment medium  wt and △ydiv 
UnknownPD-L1 expression in lung cancer and its correlation with driver mutations: a meta-analysis.
Not available
S-EPMC5578960 | biostudies-literature
ProteomicsA proteomic view of WT and △YdiU Salmonella Typhimurium under iron deficiency condition
Transition metal iron is essential for bacterial survival and growth. For pathogenic bacteria, this challenge is even more severe since human and other mammals have evolved a complicated mechanism of nutritional immunity to restrict iron availability. Preliminary research findings that iron deficien...
ORGANISM(S): Salmonella typhimurium (strain 14028s / SGSC 2262) 
2022-04-27 | PXD023378 | Pride
Differential protein expression  iron deficiency  wt and △ydiu 
TranscriptomicsDiscovery of the genes controlled by the second messenger cyclic di-GMP in Mycobacterium tuberculosis
Cyclic di-GMP (c-di-GMP) is a ubiquitous second messenger that regulates many biological processes in bacteria. The genome in Mycobacterium tuberculosis encodes a single copy of the diguanylate cyclase gene (dgc) responsible for c-di-GMP synthesis. To determine the role of c-di-GMP signaling in M. t...
ORGANISM(S): Mycobacterium tuberculosis 
2013-10-09 | E-GEOD-37973 | biostudies-arrayexpress
MetabolomicsParabacteroides distasonis ameliorates insulin resistance via activation of intestinal GPR109a
Gut microbiota plays a key role in insulin resistance (IR). Here we perform a case-control study of Chinese adults (ChiCTR2200065715) and identify that Parabacteroides distasonis is inversely correlated with IR. Treatment with P. distasonis improves IR, strengthens intestinal integrity, and reduces ...
2023-11-01 | MTBLS7943 | MetaboLights
UnknownDevelopment of predictable and high-yield CHO cell line by site-specific integration.
Not available
S-EPMC12860097 | biostudies-literature
ProteomicsExplore the proteomics characteristics of urine and serum from COVID-19 patients
we obtained the proteome profiling of serum and urine specimen collected from 50 COVID-19 patients and 40 healthy subjects. We then used TMT-labeled proteomics and quantified 1,494 and 3,854 proteins in serum and urine, respectively. We then explored the pathogenic characteristics in body fluids aft...
ORGANISM(S): Homo Sapiens 
2021-12-30 | PXD030662 |
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