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To investigate the gene expression of imiquimod induced psoriasis-like mouse model, we have employed whole genome microarray as a discovery platform to identify genes differentially expressed compared with wild type C57BL6 mouse exposed to the vehicle of imiquimod. C57BL/6J mice at 6 to 8 weeks of ...
ORGANISM(S): Mus musculus 
Mesenchymal stem cells (MSCs) exhibit immunosuppressive properties. However the homing mechanisms underlying MSC trafficking to target tissues remain elusive. Here we report that skin-derived MSCs (S-MSCs) secrete high levels of interleukin-6 (IL-6), inhibit T helper (Th)1- and Th17-cell differentia...
ORGANISM(S): Mus musculus 
The efficacy of monoclonal antibodies against either interleukin (IL)-17 or the IL-17 receptor in psoriasis therapy provides strong evidence that IL-17 is the major inflammatory mediation in this disease. However, how IL-17 induces epidermal hyperplasia in psoriasis remains largely unknown. Here, we...
ORGANISM(S): Mus musculus 
Using a whole-genome oligonucleotide microarray designed based on known and predicted indica rice genes, we investigated transcriptome profiles in developing leaves and panicles of super hybrid rice LYP9 and its parental cultivar 93-11 and PA64s. We detected 22,266 expressed genes out of 36,926 tota...
ORGANISM(S): Oryza sativa 
Purpose: Worldwide, over 350 million people are chronically infected with the hepatitis B virus (HBV) and are at increased risk of developing progressive hepatic diseases (hepatitis, cirrhosis or liver cancer). Still, the metabolic processes operational during the distinct clinical phases of a chro...
ORGANISM(S): Homo Sapiens 
This dataset contains two parts of proteomics data: a) the identification and analysis results of co-immunoprecipitation (Co-IP: Flag-asprosin/HA-PFKP) in cardiomyocytes overexpressing Flag-asprosin/HA-PFKP; b) the identification and analysis results of co-immunoprecipitation (Co-IP) using IgG as a ...
ORGANISM(S): Mus Musculus 
2025-12-24 | PXD072385 |
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