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Porcine reproductive and respiratory syndrome (PRRS), which caused by the porcine reproductive and respiratory syndrome virus (PRRSV), is a serious viral disease affecting global swine industry. At present, PRRSV vaccines fail to prevent this disease. Consequently, new antiviral strategies to compen...
ORGANISM(S): Sus scrofa domesticus (domestic pig) 
2020-12-11 | PXD016927 | Pride
Families with sequence similarity 170 members A (Fam170a) deficiency caused abnormal sperm nuclear morphology and male infertility in mice, mirroring the observation of very low Fam170a transcription in sperm of infertile men with teratozoospermia.Fam170a directly interacted with the deubiquitinatin...
ORGANISM(S): Mus Musculus 
2024-11-10 | PXD057721 |
Proteomics analysis was then applied to identify genes or pathways that could be rescued by RNAi.
ORGANISM(S): Homo Sapiens 
2022-02-01 | PXD031397 |
Global temporal quantitative proteomic and transcriptomic analysis using long-term hepatitis B virus (HBV)-infected primary human hepatocytes uncovered extensive remodeling of host proteome and transcriptome, and revealed cytopathic effects of long-term viral replication. Metabolic-, complement-, cy...
ORGANISM(S): Homo Sapiens 
2021-08-31 | PXD028190 |
Using the target protein as bait to identify interacting proteins
ORGANISM(S): Cucumis Sativus 
2025-12-22 | PXD072288 |
We re-introduced Flag-mTRADD into Tradd-/- MEFs, and identified the phosphorylation sites of TRADD which were induced by TNF and inhibited by TAK1 inhibitor 5Z7 using mass spectrometry. We found that TAK1 could mediate the phosphorylation of multiple sites in TRADD upon TNF stimulation. We next perf...
ORGANISM(S): Homo Sapiens 
2024-10-05 | PXD056588 |
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