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The perturbations of the gut microbiota and metabolites are closely associated with the progression of inflammatory bowel disease (IBD). However, inconsistent findings across studies impede a comprehensive understanding of their roles in IBD and their potential as reliable diagnostic biomarkers. ...

2026-01-28 | MTBLS8713 | MetaboLights
The gut microbiota has been associated with primary Sjogren’s syndrome (pSS), yet the biological implications of these associations are often elusive. We characterized the fecal microbiota (16S rRNA gene amplification and sequencing) and the fecal metabolome (ultrahigh-performance liquid chromatogra...
ORGANISM(S): Homo Sapiens 
2022-03-10 | PXD032289 |
Families with sequence similarity 170 members A (Fam170a) deficiency caused abnormal sperm nuclear morphology and male infertility in mice, mirroring the observation of very low Fam170a transcription in sperm of infertile men with teratozoospermia.Fam170a directly interacted with the deubiquitinatin...
ORGANISM(S): Mus Musculus 
2024-11-10 | PXD057721 |
The MDA-MB-231 cells were treated with CT-1 for 24 h. Then the cells were collected for proteomic analysis. SDT buffer was used for sample lysis and protein extraction. Protein digestion by trypsin was performed according to filter-aided sample preparation (FASP) procedure described by Matthias Mann...
ORGANISM(S): Homo Sapiens 
2024-10-30 | PXD057337 |
Skin is a thin, stratified tissue covering the entire body. It is microscopically defined by layers of epidermal epithelial cells separated from cells in the dermis by a basement membrane (BM), the skin’s extracellular matrix (ECM). The skin’s ECM binds the layers together to form the tissue’s organ...
ORGANISM(S): Sus Scrofa 
2019-07-01 | PXD014454 |
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