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TranscriptomicsRBBP6 isoforms regulate the human polyadenylation machinery and modulate expression of mRNAs with AU-rich 3' UTRs
Polyadenylation of mRNA precursors is mediated by a large multisubunit protein complex. Here we show that RBBP6 (retinoblastoma-binding protein 6), identified initially as an Rb- and p53-binding protein, is a component of this complex and functions in 3' processing in vitro and in vivo. RBBP6 associ...
ORGANISM(S): Homo sapiens 
2014-11-06 | E-GEOD-63036 | biostudies-arrayexpress
UnknownTLE4 promotes colorectal cancer progression through activation of JNK/c-Jun signaling pathway.
Not available
S-EPMC4823078 | biostudies-literature
UnknownGlycyrrhetinic acid induces cytoprotective autophagy via the inositol-requiring enzyme 1α-c-Jun N-terminal kinase cascade in non-small cell lung cancer cells.
Not available
S-EPMC4791276 | biostudies-literature
TranscriptomicsFunctional Annotation of the Bovine Genome
The goal of the proposed project is to generate high-quality detailed transcript and chromatin status datasets from a comprehensive set of bovine tissues, developmental stages, and cells through a set of rationally selected assays. Experimental data generated by the project have been analyzed using ...
ORGANISM(S): Bos taurus 
2022-10-13 | E-MTAB-12052 | biostudies-arrayexpress
MetabolomicsNon-invasive urinary metabolomic profiles discriminate biliary atresia from infantile hepatitis syndrome
INTRODUCTION: Neonatal cholestatic disorders are a group of hepatobiliary diseases occurring in the first 3 months of life. The most common causes of neonatal cholestasis are infantile hepatitis syndrome (IHS) and biliary atresia (BA). The clinical manifestations of the two diseases are ...
2019-06-25 | MTBLS689 | MetaboLights
UnknownCTLA-4 and MDR1 polymorphisms increase the risk for ulcerative colitis: A meta-analysis.
Not available
S-EPMC4566373 | biostudies-literature
UnknownComputational and Experimental Study of Li-Doped Ionic Liquids at Electrified Interfaces.
Not available
S-EPMC7526643 | biostudies-literature
UnknownRandomized phase III trial of induction chemotherapy with docetaxel, cisplatin, and fluorouracil followed by surgery versus up-front surgery in locally advanced resectable oral squamous cell carcinoma.
Not available
S-EPMC5569675 | biostudies-literature
UnknownAnisotropic Carbon Nanotube Structures with High Aspect Ratio Nanopores for Li-Ion Battery Anodes.
Not available
S-EPMC8240089 | biostudies-literature
UnknownChloramphenicol causes mitochondrial stress, decreases ATP biosynthesis, induces matrix metalloproteinase-13 expression, and solid-tumor cell invasion.
Not available
S-EPMC2886854 | biostudies-literature
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