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ProteomicsMass spectrometry-based proteomics reveals potential roles of NEK9 and MAP2K4 in resistance to PI3K inhibitors in triple negative breast cancer

Filip Mundt, Sandeep Rajput, Shunqiang Li, Kelly Ruggles, Arshag D. Mooradian, Philipp Mertins, Michael A. Gillette, Karsten Krug, et al., Cancer Res. 2018 May 15;78(10):2732-2746. doi: 10.1158/0008-5472.CAN-17-1990.

Activation of phosphoinositide 3-kinase (PI3K) signaling is frequently obs...

ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2018-10-19 | MSV000083050 | MassIVE
UnknownA Functional Interaction Between Na,K-ATPase β2-Subunit/AMOG and NF2/Merlin Regulates Growth Factor Signaling in Cerebellar Granule Cells.
Not available
S-EPMC6815692 | biostudies-literature
ProteomicsProteogenomic Integration Reveals Therapeutic Targets in Breast Cancer Xenografts
Huang K, Li S, Mertins P, Cao S, Gunawardena HP, Ruggles KV, et al., (2017) Nature Communications | 8:14864 | DOI: 10.1038/ncomms14864 | http://www.nature.com/articles/ncomms14864

Recent advances in mass spectrometry (MS) hav...

ORGANISM(S): Homo Sapiens (ncbitaxon:9606) Mus Musculus (ncbitaxon:10090) 
2019-08-28 | MSV000084249 | MassIVE
MetabolomicsChemodiverse cell systems responses to UV in an algal sister of land plants

Plant terrestrialization necessitated overcoming a barrage of stressors. Embryophytes (land plants) use an integrated response network to adjust their molecular physiology in response to terrestrial stressors—one of the important stressors is UV irradiance. The zygnematophytes are the closest str...

2026-07-01 | MTBLS8088 | MetaboLights
UnknownAndrogen receptor function and targeted therapeutics across breast cancer subtypes.
Not available
S-EPMC9664788 | biostudies-literature
UnknownWhole genome sequence analysis of low-density lipoprotein cholesterol across 246 K individuals.
Not available
S-EPMC12418676 | biostudies-literature
TranscriptomicsGene expression profiling of novel antigen presenting cells (APC) inducing pathogenic T helper cells of lupus
In lupus autoimmunity, pathogenic IgG autoantibodies that fix complement and bind FcGammaR on inflammatory cells, are produced with help from T helper (Th1 and Th17) cells specific for peptides from nucleosomes of apoptotic cells; and these Th cells also infiltrate vital organs (1-9). Macrophages (...
ORGANISM(S): Mus musculus 
2012-06-20 | E-GEOD-36284 | biostudies-arrayexpress
UnknownPaper 4: a review of reporting and disseminating approaches for rapid reviews in health policy and systems research.
Not available
S-EPMC9338534 | biostudies-literature
UnknownRegulation of the localisation and function of the oncogene LYRIC/AEG-1 by ubiquitination at K486 and K491.
Not available
S-EPMC4013555 | biostudies-literature
UnknownChronotype and cellular circadian rhythms predict the clinical response to lithium maintenance treatment in patients with bipolar disorder.
Not available
S-EPMC6333516 | biostudies-literature
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