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Collateral lethality occurs when loss of one paralog renders cancer cells dependent on the remaining paralog. Combining genome scale CRISPR/Cas9 screens coupled with RNA-sequencing in over 900 cancer cell lines, we found that cancers of nervous system lineage, including adult and pediatric gliomas a...
ORGANISM(S): Homo sapiens (Human) 
2022-09-06 | PXD030599 | Pride
Genome-wide DNA methylation profile of human spermatozoa using the meDIP technique and massively parallel sequencing. DNA methylation is an indispensible epigenetic modification required for regulating the expression of mammalian genomes. Immunoprecipitation-based methods for DNA methylome analysis ...
ORGANISM(S): Homo sapiens 
2011-02-05 | GSE25686 | GEO
This is the model of the in vitro DNA oscillator called oligator with the optmized set of parameters described in the article: Programming an in vitro DNA oscillator using a molecular networking strategy. Montagne K, Plasson R, Sakai Y, Fujii T, Rondelez Y. Mol Syst Biol. 2011 Feb 1...
2024-09-02 | BIOMD0000000315 | BioModels
Identification of hair cycle-associated genes from time-course gene expression profile data by using replicate variance. Proc. Natl. Acad. Sci. USA. (2004)
ORGANISM(S): Mus musculus 
We found many binding sites for FNR under glucose fermentative anaerobic growth conditions. Also, many binding sites were identified for M-OM-^C70 under both aerobic and anaerobic growthin conditions. Descirbed in the manuscript "Genome-scale Analysis of E. coli FNR Reveals the Complexity of B...
ORGANISM(S): Escherichia coli str. K-12 substr. MG1655 
This is a dataset generated by the Drosophila Regulatory Elements modENCODE Project led by Kevin P. White at the University of Chicago. It contains genome-wide binding profile of the factor KW3-Pcl-D2 from D.sim_WPP generated by ChIP and analyzed on Illumina Genome Analyzer. For data usage terms an...
ORGANISM(S): Drosophila simulans 
This is a dataset generated by the Drosophila Regulatory Elements modENCODE Project led by Kevin P. White at the University of Chicago. It contains genome-wide binding profile of the factor H3K27me3 from D.sim_WPP generated by ChIP and analyzed on Illumina Genome Analyzer. For data usage terms and ...
ORGANISM(S): Drosophila simulans 
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