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GenomicsSubsets of visceral adipose tissue nuclei with discrete levels of 5-hydroxymethylcytosine
We explored the hypothesis that adipose tissue contains epigenetically distinct subpopulations of adipocytes that are differentially potentiated to record cellular memories of their environment. Adipocytes are large, fragile, and technically difficult to efficiently isolate and fractionate. We devel...
ORGANISM(S): Sus scrofa 
2016-07-20 | E-GEOD-73684 | biostudies-arrayexpress
ProteomicsProteomics of antler protein extract and rat skin tissue
In this experiment, a rat model of full-thickness skin resection was used to observe the effect of antler protein extract ( PAE ) on wound healing, and its pharmacodynamic effect on wound healing and possible regulatory mechanism were further analyzed. Rats were randomly divided into PAE group and N...
ORGANISM(S): Theileria sp. ex Hiroshima Sika Deer 
2026-02-09 | PXD037328 | Pride
2.deer antler protein extract Rat skin tissue Proteomics Wound healing 
UnknownReusable and Practical Biocomposite Based on Sphingopyxis sp. YF1 and Polyacrylonitrile-Based Carbon Fiber for the Efficient Bioremediation of Microcystin-LR-Contaminated Water.
Not available
S-EPMC10819031 | biostudies-literature
ProteomicsQuantitative Proteome Profiling of Maize Root zones Provides Insight into the Proteins Associated with Enhance Water Uptake in Maize
In order to get a better understanding of protein functions related to water uptake in maize, we investigated the proteome dynamics of cv. Anyu308 root system at three key zones divided into Upper root (0cm-20cm), Middle root (20cm-40cm), and Lower root (40cm-60cm) by label-free quantitative shotgun...
ORGANISM(S): Zea Mays 
2021-05-26 | PXD026269 |
GenomicsGenome-wide Analysis of Chromatin Interactions in Human Cells
Millions of cis-regulatory sequences have recently been found in the human genome, but the function of most cis-elements are not yet clear, in part due to the difficulty in determining their regulatory targets, which are often located millions of base pairs away and separated by one or more unrelate...
ORGANISM(S): Homo sapiens 
2013-10-20 | E-GEOD-43070 | biostudies-arrayexpress
ProteomicsHuman placental tissue LC-MS/MS
This project aimed at missing protein identification from human placental tissue, combining sample preparation and mass spectrometry technology development.For sample preparation, low molecular proteins were enriched by C18 solid phase extraction, SDS-PAGE and MWCO filter. For LC-MS/MS analysis, mic...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2020-10-29 | MSV000086385 | MassIVE
MetabolomicsProduction of chain-extended cinnamoyl compounds by overexpressing two adjacent cluster-situated LuxR regulators in Streptomyces globisporus C-1027

Natural products from microorganisms are important sources for drug discovery. With the development of high-throughput sequencing technology and bioinformatics, a large amount of uncharacterized biosynthetic gene clusters (BGCs) in microorganisms have been found, which show the potential for nove...

2023-09-06 | MTBLS5152 | MetaboLights
GenomicsOpposing actions of IL-2 and IL-21 on Th9 differentiation correlate with their differential regulation of BCL6 expression
Interleukin 9 (IL-9) is a γc-family cytokine that is highly produced by T-helper 9 (Th9) cells and regulates a range of immune responses, including allergic inflammation. Here we show that IL-2–JAK3–STAT5 signaling is required for Th9 differentiation, with critical STAT5 binding sites in the Il9 (th...
ORGANISM(S): Mus musculus 
2014-02-20 | E-GEOD-41317 | biostudies-arrayexpress
UnknownRanking Cancer Proteins by Integrating PPI Network and Protein Expression Profiles.
Not available
S-EPMC6339728 | biostudies-literature
UnknownDevelopment and validation of a model for predicting in-hospital mortality in patients with sepsis-associated kidney injury receiving renal replacement therapy: a retrospective cohort study based on the MIMIC-IV database.
Not available
S-EPMC11570588 | biostudies-literature
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