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Cyclic di-GMP (c-di-GMP) is a well-known second messenger that plays a key role in many physiological processes in bacteria. The synthesis of lipids is essential for bacterial biofilm formation. However, whether c-di-GMP signaling modulates the synthesis of lipid and further regulates biofilm for...

2023-12-12 | MTBLS7053 | MetaboLights
Airway remodeling is a critical pathological process that influences the progression of chronic obstructive pulmonary disease(COPD). To better study small airway remodeling in COPD, we employed advanced techniques such as decellularized scaffolds and proteomics to analyze compositional changes in th...
ORGANISM(S): Mus musculus (Mouse) 
2025-05-07 | PXD058944 | Pride

Background: Staphylococcus aureus (SA) remains a global health threat due to its increasing drug resistance and intracellular persistence, which compromise the efficacy of conventional antibiotics. Host-directed therapy (HDT) has emerged as a promising alternative by modulating host...

2026-02-25 | MTBLS13930 | MetaboLights
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