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To investigate the mechanisms underlying fluctuating IRE1α phosphorylation under chronic endoplasmic reticulum stress, we performed co-immunoprecipitation coupled with mass spectrometry (IP-MS) to identify IRE1α-interacting proteins. Protein complexes were analyzed by LC-MS/MS, followed by bioinform...
ORGANISM(S): Homo Sapiens 
2026-01-30 | PXD073899 |
Analysis of c-Myb-regulation of gene expression. The hypothesis tested in the present study was that c-Myb influences the expression of specific sets of genes that are involved in cell cycle, DNA replication, recombination and repair. Results provide important information on c-Myb-responsive genes ...
ORGANISM(S): Homo sapiens 
Human glioma pathogenesis-related protein 1 (GLIPR1) and its mouse counterpart, Glipr1 are downregulated in prostate cancer (PCa) and other malignant cell lines, owing partly to methylation in the gene’s regulatory region. Loss of Glipr1 function predisposed mice to tumorigenesis. Restoration of GLI...
ORGANISM(S): Homo sapiens 
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