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MetabolomicsPTER is an N-acetyltaurine hydrolase that regulates feeding and obesity

Taurine is a conditionally essential micronutrient and one of the most abundant amino acids in humans1-3. In endogenous taurine metabolism, dedicated enzymes are involved in biosynthesis of taurine from cysteine as well as the downstream metabolism of secondary taurine metabolites4,5. One such ta...

2024-09-11 | MTBLS10408 | MetaboLights
TranscriptomicsA Whole Transcriptional Linkage Analysis of Gene Co-Regulation in Insecticide Resistant House Flies, Musca domestica
Illumina HiSeq 2000 RNASeq was conducted on the mRNA fraction of three adult female Musca domestica strains. Two strains were the insecticide susceptible strains CS and aabys, which has five distinct recessive morphological markers, one on each of the five autosomes in M. domestica. The third strain...
ORGANISM(S): Musca domestica 
2014-01-02 | E-GEOD-39327 | biostudies-arrayexpress
ProteomicsCoro1a promotes the multivesicular body and plasma membrane fusion by facilitating PKM2-mediated SNAP-23 phosphorylation
During the formation of endosomal pathway-dependent extracellular vesicles (EVs), intraluminal vesicles in multivesicular bodies (MVBs) fuse with the plasma membrane (PM), releasing intraluminal vesicles to produce exosomes. Soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNAR...
ORGANISM(S): Homo Sapiens 
2025-12-07 | PXD071700 |
ProteomicsTransketolase promotes MAFLD by limiting inosine-induced mitochondrial activity (Proteomics)
Metabolic dysfunction-associated fatty liver disease (MAFLD) has a global prevalence of about 25% and no approved therapy. Using metabolomic and proteomic analyses, we identified high expression of hepatic transketolase (TKT), a metabolic enzyme of the pentose phosphate pathway, in human and mouse M...
ORGANISM(S): Homo Sapiens 
2024-02-26 | PXD050130 |
ProteomicsGS2-SUG1 module-mediated control of grain size and weight in rice
SUG1 associates with multiple transcription factors, such as OsBZR1, OsMADS56 and OsSPL13, to control grain size through GA and BR signaling as well as growth pathways.
ORGANISM(S): Oryza Sativa Japonica Group 
2024-05-15 | PXD052270 |
TranscriptomicsPatch-seq Sequencing of mouse glioma cells
Mouse glioma cells are recorded through patch-seq first, and the cytosol was collected afterwards, and the whole transcriptomic RNA library was reconstructed and sequenced afterwards.
ORGANISM(S): Mus musculus 
2026-05-31 | E-MTAB-17027 | biostudies-arrayexpress
ProteomicsQuantitative proteomics of Pseudomonas protegens Pf-5 treated with pyoluteorin and ΔphlG strain
To acquired insights into the pyoluteorin-mediated physiological process of P. fluorescens, label-free quantitative proteomics was used to compare the expression differences between the whole proteome of Pf-5 with and without pyoluteorin. To further investigate the importance of PhlG in physiologica...
ORGANISM(S): Pseudomonas Protegens Pf-5 
2023-01-09 | PXD039317 |
ProteomicsLyn attenuates cisplatin-induced acute kidney injury by inhibition of RIPK1-mediated apoptosis and necroptosis
Our study revealed that Lyn protects from cisplatin-induced nephrotoxicity by suppressing RIPK1-mediated apoptosis, necroptosis and inflammation.
ORGANISM(S): Mus Musculus 
2026-05-16 | PXD078460 |
ProteomicsSerum proteomics of T2DM individuals with HFpEF after dapagliflozin treatment by tandem mass spectrometry
A quantitative proteomic profiling by TMT was performed on serum of T2DM individuals with or without dapagliflozin treatment
ORGANISM(S): Homo Sapiens 
2022-10-18 | PXD037538 |
ProteomicsProteomic Profiling Reveals Indicative Biomarkers for Diabetic Retinopathy with Diabetic Kidney Disease
Diabetes retinopathy (DR) and diabetes kidney disease (DKD) are the complications of diabetes and causing serious health and economic burden to society. However, identification and characterization of early biomarkers for DKD, especially for non-proliferative DR (NPDR) patients with DKD, are still l...
ORGANISM(S): Homo Sapiens 
2022-08-19 | PXD036172 |
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