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ProteomicsA phosphatase-like nanomaterial promotes autophagy and reprograms macrophage for cancer immunotherapy
Macrophages are very plastic and play key roles in maintenance of tissue homeostasis. In cancer progression, macrophages also take parts through all the processes, from the initiation, progression, to the final tumor metastasis. Although energy deprivation and autophagy are widely used for cancer th...
ORGANISM(S): Mus musculus (Mouse) 
2024-08-10 | PXD051695 | Pride
Raw264.7 Mice Phospho-proteins Lc-ms/ms 
ProteomicsGlioblastoma-derived migrasomes promote migration and invasion by releasing PAK4 and LAMA4
Almost all high-grade gliomas, particularly glioblastoma (GBM), are highly migratory and aggressive. Migrasomes are organelles produced by highly migratory cells capable of mediating intercellular communication. Thus, GBM cells may produce migrasomes during migration. However, it remains unclear whe...
ORGANISM(S): Homo Sapiens 
2024-11-05 | PXD057558 |
ProteomicsMethylcobalamin protects against liver failure via engaging gasdermin E
To probe the binding sites of MeCbl on GSDME, 0.4 μM recombinant human GSDME (CSB-EP006766HU) purchased from CUSABIO (Wuhan, China) was incubated with 10 μM MeCbl in 100 μL buffer (20 mM HEPES, 150 mM NaCl and 50 μM DPA) at room temperature for 2 h and protected from light. 0.4 μM recombinant human ...
ORGANISM(S): Homo Sapiens 
2024-11-11 | PXD057768 |
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