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GenomicsAKT/mTOR/HER/PI3K family proteins and phospho-proteins as predictors of pCR for early stage breast cancer patients treated with the AKT inhibitor MK2206 in the I-SPY 2 TRIAL (NCT01042379)
AKT/mTOR/HER/PI3K family proteins and phospho-proteins as predictors of pCR for early stage breast cancer patients treated with the AKT inhibitor MK2206 in the I-SPY 2 TRIAL (NCT01042379)
PRJNA632851 | ENA
GenomicsRAID allows multiplexed quantification of intracellular (phospho-)proteins and transcriptomes from fixed single cells
RAID allows multiplexed quantification of intracellular (phospho-)proteins and transcriptomes from fixed single cells
PRJNA476686 | ENA
UnknownCombined quantification of intracellular (phospho-)proteins and transcriptomics from fixed single cells.
Not available
S-EPMC6365588 | biostudies-literature
UnknownAnalyzing the influence of kinase inhibitors on DNA repair by differential proteomics of chromatin-interacting proteins and nuclear phospho-proteins.
Not available
S-EPMC5762299 | biostudies-literature
UnknownThe Sir4 H-BRCT domain interacts with phospho-proteins to sequester and repress yeast heterochromatin.
Not available
S-EPMC6792019 | biostudies-literature
ProteomicsSir4 H-BRCT domain interacts with multiple phospho-proteins to regulate heterochromatic repression
In Saccharomyces cerevisiae, the Silent Information Regulator (SIR) proteins Sir2/3/4 form a complex suppressing transcription of genes at subtelomeric regions and the homothallic mating type (HM) loci. Here we identify a non-canonical BRCA1 C-terminal domain (H-BRCT) in Sir4 which is responsible fo...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2019-09-13 | PXD014119 | Pride
Tom1 Sir complex Heterochromatin Brct Dbf4 
UnknownThe phospho-docking protein 14-3-3 regulates microtubule-associated proteins in oocytes including the chromosomal passenger Borealin.
Not available
S-EPMC9203013 | biostudies-literature
UnknownGuanylate kinase domains of the MAGUK family scaffold proteins as specific phospho-protein-binding modules.
Not available
S-EPMC3243629 | biostudies-literature
ProteomicsAKT/mTOR/HER/PI3K family proteins and phospho-proteins as predictors of pCR for early stage breast cancer patients treated with the AKT inhibitor MK2206 in the I-SPY 2 TRIAL (NCT01042379)
The AKT inhibitor MK2206 (M) was one of the experimental agents evaluated in I-SPY 2, a neoadjuvant platform trial for high risk, early stage breast cancer, and graduated in the HER2+, HR-, and HR-HER2+ signatures. Based on the hypotheses that since MK2206 is an enzymatic inhibitor of AKT, response ...
ORGANISM(S): Homo sapiens 
2020-09-20 | GSE150575 | GEO
UnknownModulation of phospho-proteins by interferon-alpha and valproic acid in acute myeloid leukemia.
Not available
S-EPMC6571093 | biostudies-literature
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