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ProteomicsMCPIP2 competes with IGF2BP1 binding to common stem-loop structure in the 3’UTRs of pro-angiogenic genes for suppressing breast tumor angiogenesis-2
This study was performed according to RNA pull-down assay using biotin-labeled WT RNA probe (with stem-loop structure) or mutant RNA probe (without stem-loop structure) and streptavidin-coated Dynabeads in human breast tumor cell MDA-MB-468, and then the pulled down proteins were isolated by SDS-PA...
ORGANISM(S): Homo Sapiens 
2024-06-05 | PXD052920 |
ProteomicsMCPIP2 competes with IGF2BP1 binding to common stem-loop structure in the 3’UTRs of pro-angiogenic genes for suppressing breast tumor angiogenesis
This study was performed according to protein pull-down assay using GFP-coated beads in GFP-MCPIP2 fusion protein expressed MDA-MB-468 cells, and then the pulled down proteins were isolated by running SDS-PAGE and silver staining, and identified by high resolution mass spectrometry.
ORGANISM(S): Homo Sapiens 
2024-06-05 | PXD052919 |
ProteomicsIntegrative proteomic and phosphoproteomic analyses reveal complex mechanisms of reproductive diapause in Bombus terretris queens (proteome)
Reproductive diapause is the overwintering strategy for Bombus terrestris, which is an important pollinator for agricultural production. However, the precise mechanisms of the reproductive diapause in bumble bees remain largely unclear. Here, a combination analyses of proteomics and phosphoproteomic...
ORGANISM(S): Bombus Terrestris 
2022-05-28 | PXD034198 |
ProteomicsIntegrative proteomic and phosphoproteomic analyses reveal complex mechanisms of reproductive diapause in Bombus terretris queens (phosphoproteome)
Reproductive diapause is the overwintering strategy for Bombus terrestris, which is an important pollinator for agricultural production. However, the precise mechanisms of the reproductive diapause in bumble bees remain largely unclear. Here, a combination analyses of proteomics and phosphoproteomic...
ORGANISM(S): Bombus Terrestris 
2022-05-28 | PXD034199 |
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