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ProteomicsPhosphopeptide mass spectrometry analysis of LATS2 identifies a second autophosphorylation site in HEK293A cells
This dataset contains phosphopeptide LC-MS/MS data generated from human LATS2 overexpressed in HEK293A cells. The study was designed to identify LATS2 phosphorylation sites and to support phosphopeptide mapping of LATS2 autophosphorylation, with particular attention to the kinase-domain CLS site. Im...
ORGANISM(S): Homo sapiens (Human) 
2026-06-29 | PXD076693 | Pride
Homo sapiens  hek293a  lats2  hippo pathway  autophosphorylation  phosphopeptide  lc-ms/ms  kinase 
ProteomicsLysine methylation promotes NFAT5 activation upon EGFR activation and predicts response to temozolomide
Temozolomide (TMZ) therapy offers minimal clinical benefits in patients with glioblastoma multiforme (GBM) with high EGFR activity, underscoring the need for effective combination therapy. Here, we show that tonicity-responsive enhancer binding protein (NFAT5) lysine methylation, is a determinant of...
ORGANISM(S): Homo Sapiens 
2022-11-01 | PXD037869 |
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