Sort   by:  
 Page size 
TranscriptomicsMitochondrial functional aberrations in a mouse model of non-ischemic heart failure
We characterized the metabolic and cardiac mitochondrial function in a mouse model of non-ischemic HF. Inhibition of nitric oxide synthesis and hypertension, which often present together, are two important risk factors in human non-ischemic HF. Compared with L-NAME L-NG-Nitroarginine methyl ester (L...
ORGANISM(S): Mus musculus 
2016-01-19 | E-GEOD-72132 | biostudies-arrayexpress
MetabolomicsPlasma metabolomic profiling reveals altered metabolic pathways associated with idiopathic hyperaldosteronism
This study investigated plasma metabolic alterations associated with idiopathic hyperaldosteronism using untargeted liquid chromatography coupled with high-resolution mass spectrometry. Plasma samples from patients with idiopathic hyperaldosteronism and healthy controls were analyzed using a Vanquis...
2026-08-07 | MTBLS15210 | MetaboLights
MetabolomicsTubular insulin-induced gene 1 deficiency promotes NAD+ consumption and exacerbates kidney fibrosis

Profibrotic proximal tubular (PT) were identified as a unique phenotype of PTCs in renal fibrosis by single-cell RNA sequencing (scRNA-seq). Controlling the process of renal fibrosis requires understanding how to manage the S1 subset's branch to the S3 subset rather than to the profibrotic PT sub...

2024-05-28 | MTBLS9985 | MetaboLights
UnknownNanoscale distribution of Bi atoms in InP1-xBix.
Not available
S-EPMC5612989 | biostudies-literature
UnknownNucleus Accumbens Corticotropin-Releasing Hormone Neurons Projecting to the Bed Nucleus of the Stria Terminalis Promote Wakefulness and Positive Affective State.
Not available
S-EPMC11607243 | biostudies-literature
TranscriptomicsIntra-MZ pair discordance and longitudinal variation of whole-genome scale DNA methylation in adults
In this study, we used Illumina Infinium HumanMethylation450 Beadchips to compare DNA methylation profiles in blood from 10 pairs of MZ twins and 8 individuals recruited at 0, 3, 6, and 9 months. MZ Group (Group A) contained 10 pairs of MZ twins ranging from 23 to 74 years old, including 8 female an...
ORGANISM(S): Homo sapiens 
2013-10-30 | E-GEOD-51388 | biostudies-arrayexpress
ProteomicsHost defesen effects of vitamin D
To study the pleiotropic effects of vitamin D in airway host defense, we use airway epithelial organoids cultured on air-liquid interface (ALI), originating from three chronic rhinosinusitis patients, marking as N66, N67 and N69, respectively. 24 hours prior to infection of Staphylococcus Aureus or ...
ORGANISM(S): Homo Sapiens 
2022-02-28 | PXD031956 |
UnknownBAG5 regulates HSPA8-mediated protein folding required for sperm head-tail coupling apparatus assembly
Not available
S-SCDT-10_1038-S44319-024-00112-X | biostudies-other
TranscriptomicsDevelopmental ablation of Id1 and Id3 genes in the vasculature leads to postnatal cardiac phenotypes
Rationale: The Id1 and Id3 genes play major roles during cardiac development, despite their expression being confined to non-myocardial layers (endocardium â?? endothelium - epicardium). We previously described that Id1â??/â??Id3â??/â?? double knockout (dKO) mouse embryos die at mid-gestation from m...
ORGANISM(S): Mus musculus 
2010-10-07 | E-GEOD-21924 | biostudies-arrayexpress
ProteomicsMulti-omics uncovers immune-modulatory molecules in plasma contributing to resistance exercise-ameliorated locomotor disability after incomplete spinal cord injury_mouse data
We established a weight-loaded ladder-climbing mouse model to mimic the physiological effects of resistance exercise, and we analyzed the plasma proteome.
ORGANISM(S): Mus Musculus 
2025-01-26 | PXD060217 |
Sort   by:  
 Page size