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UNIPROT ID/AC

P05132 (3)
Q3U214 (3)

CHEBI ID

CHEBI:15428 (1)
CHEBI:15429 (1)
CHEBI:15584 (1)
CHEBI:15741 (1)
CHEBI:15756 (1)
CHEBI:15940 (1)
CHEBI:16000 (1)
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Metabolite Name

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Glycerol (1)

IsPrivate

False (3)

Modelling Approach

Ordinary differential equation model (3)

Modification

4-tetrahydrothiazine-3-carboxylic acid (1)

Study type

Transcription profiling by array (7)
ChIP-chip by tiling array (3)
ChIP-chip by array (2)
RNA-seq of coding RNA from single cells (2)
RNA-seq of coding RNA (2)
Unknown experiment type (1)
ChIP-seq (1)
Methylation profiling by array (1)

Release Date

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2022 (125)
2021 (124)
2024 (109)
2020 (109)
2025 (106)
2019 (93)
2015 (90)
2018 (87)
2017 (76)
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2012 (40)
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2008 (6)
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2004 (1)
2003 (1)

Lab affiliation

State Key Laboratory of Veterinary Etiological Biology, Key Laboratory of Veterinary Parasitology of Gansu Province, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, Gansu Province 730046, PR China (3)
Head, Dept of Immunology, Institute for Cancer Research, Oslo University Hospital Radiumhospitalet, Ullernchausséen 70, 0379 Oslo, Norway (2)
College of Veterinary Medicine, Lanzhou University, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, China. (1)
Department of Anatomy and Cell Biology, University of Florida College of Medicine, Gainesville, FL, 32610, USA. (1)
NINDS Clinical Proteomics Unit National Institutes of Health (1)
PI The Wistar Institute, Philadelphia, PA, USA; (1)
School of Biomedical Sciences, The Chinese University of Hong Kong, Hong Kong SAR (1)
State Key Laboratory of Pharmaceutical Biotechnology, Model Animal Research Center of Medical School and Gulou Hospital affiliated Medical School, Nanjing University (1)
Yale University (Keck MS & Proteomics Resource) (1)

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TCR-engineered T cells targeting a shared β-catenin mutation eradicate solid tumors in vivo

CTNNB1/ ꞵ-catenin is mutated in 3.3% of solid cancers, with several recurrent gain-of-function mutations occurring early during cancer formation. This includes the shared driver mutation CTNNB1S37F, estimated to occur in >7000 new cancer cases in 2024 in the US. However, to offer attractive immunoth...

ORGANISM(S): Homo sapiens (Human)

2025-07-15 | PXD054276 | Pride