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Cell signaling pathways are enriched for biological processes crucial for cellular communication, response to external stimuli, and metabolism. Here, we conducted a cell signaling-focused CRISPR screen and identified cytochrome c oxidase subunit 4I1 (COX4I1) as a novel vulnerability in acute myeloid...
ORGANISM(S): Homo sapiens (Human) 
2025-05-06 | PXD050739 | Pride
Human embryonic stem cells (hESCs) have capacity of self-renewal and multi-lineage differentiation into derivatives of three germ layers that are of clinical importance for regeneration medicine. Despite the significant progress of hESCs study for clinical application, factors responsible for mainta...
ORGANISM(S): Homo Sapiens (human) 
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