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Osteosarcoma (OS), a highly malignant bone tumor, is characterized by rapid progression and poor prognosis, with lipid metabolic reprogramming playing a crucial role in its pathogenesis. This study investigates the role of RHBDL2 in OS progression and its therapeutic potential. We demonstrate that R...
ORGANISM(S): Homo Sapiens 
2025-03-31 | PXD062405 |
Metastatic BRAFV600E colorectal cancer (CRC) confers poor prognosis and run into a bottleneck in the current treatment strategies. To identify regulatory pathways independent of the MAPK pathway in BRAFV600E CRC, we performed CRISPR-Cas9 screening, and and find targeting glutathione peroxidase 4 (GP...
ORGANISM(S): Homo Sapiens 
2024-11-25 | PXD058213 |
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