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MetabolomicsCell Membrane Remodeling Mediates Polymyxin B Resistance in Klebsiella pneumoniae: An Integrated Proteomics and Metabolomics Study
Polymyxin B (PB) is introduced into the clinic as the last-line therapy against carbapenem-resistant Klebsiella pneumoniae (CRKP). Unfortunately, increased resistance to PB in Klebsiella pneumoniae (K. pneumoniae) has threatened global health. Resistance of K. pneumoniae ...
2022-03-04 | MTBLS4132 | MetaboLights
UnknownO-GlcNAcylation stabilized WTAP promotes GBM malignant progression in an N6-methyladenosine-dependent manner.
Not available
S-EPMC12083224 | biostudies-literature
UnknownNew risk score for predicting progression of membranous nephropathy.
Not available
S-EPMC6368730 | biostudies-literature
Proteomics,MultiomicsProteomics of EBV-infected lytic and refractory cells
Most humans are infected with Epstein-Barr virus (EBV), a cancer-causing virus. While EBV generally persists silently in B lymphocytes, periodic lytic (re-)activation of latent virus is central to its life cycle and to most EBV-related diseases. However, a substantial fraction of EBV-infected B cell...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2016-07-22 | MSV000079993 | MassIVE
ProteomicsTMT-based proteomic approach was used to compare the liver protein expression profiles of cancer cachexia mice and healthy control mice
TMT-based proteomic approach was used to compare the liver protein expression profiles of cancer cachexia mice and healthy control mice.
ORGANISM(S): Mus Musculus 
2021-01-11 | PXD023497 |
ProteomicsPhosphoproteomic in soleus and biceps femoris muscle
We used phosphoproteomic profiling of slow-twitch (soleus, SOL) and fast-twitch (biceps femoris, BF) muscle to identify differences between these muscle types.
ORGANISM(S): Sus Scrofa Domesticus 
2022-08-16 | PXD036066 |
MetabolomicsUridine restores oocyte quality and mitigates female reproductive aging by inhibition of ferroptosis in mice

Advanced maternal age is a key factor in female infertility, primarily due to declines in ovarian reserve and oocyte quality. However, the metabolic mechanisms underlying reproductive aging are still poorly understood. Here, we show that uridine levels in the plasma and ovaries of aged mice are s...

2026-03-03 | MTBLS13957 | MetaboLights
ProteomicsRNA-Binding Motif protein 6 is a candidate serum biomarker for pancreatic cancer
Early diagnosis is crucial to improve outcomes for pancreatic cancer (PC) patients, however the lack of specific and validated biomarkers for the disease remains challenging. In this study, we analyzed the serum proteome of 12 PC patients and 76 healthy controls (HC), using magnetic bead-based weak ...
ORGANISM(S): Homo Sapiens 
PXD013626 |
ProteomicsProteomic analysis of rG4_A selectively degraded proteins through the proteasome
To explore the effects of rG4-PROTACs on the whole proteome, Hela cells were treated with blank (empty transfection control), rG4 mut_A, rG4_A, or rG4_A plus MG132, and a proteomic analysis was included in the subproject
ORGANISM(S): Homo Sapiens 
2024-11-21 | PXD058113 |
ProteomicsThe proteome data of human mesenchymal stem cell derived from healthy donors
The protein samples stored at -80 °C were thawed and treated with lysis buffer (8M urea, 1% protease inhibitor, 50mM NH4HCO3) for 5 minutes in room temperature. After ultrasonic cracking on ice and centrifugation at 14000g for 10 min at 20 °C, the amount of total protein of each MSC sample was detec...
ORGANISM(S): Homo Sapiens 
2023-06-12 | PXD033812 |
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