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UnknownLocalized DNA tetrahedrons assisted catalytic hairpin assembly for the rapid and sensitive profiling of small extracellular vesicle-associated microRNAs.
Not available
S-EPMC9714172 | biostudies-literature
ProteomicsThe length distribution of MHC-I binding peptides
The current study provides an opportunity to identify specific MHC I motifs in vitro. The combination of random peptide library, LC-MS/MS and De Novo Sequencing can be an important complement to the identification of MHC I motif. Insight into the length distribution of MHC-I binding peptides helps u...
ORGANISM(S): Sus scrofa domesticus (domestic pig) 
2022-02-25 | PXD020818 | Pride
Swine mhc class i，random peptide library，lc-ms/ms，de novo sequencing 
TranscriptomicsExpression data from different photosynthetic rate in Populus.
Despite the significance of nucleus genes in plant growth and development, little is known of the molecular bases of regulation of photosynthesis in woody plants.Hence discovering the genetic basis for photosynthesis related phenotypic variation and identifying the major genes controlling these comp...
ORGANISM(S): (Populus alba x Populus glandulosa) x Populus tomentosa 
2014-05-31 | E-GEOD-47105 | biostudies-arrayexpress
ProteomicsPeptidomes of MHC Class I Allotypes Illustrate the Peptide binding Plasticity Leading by Micropolymorphism
The current study provides an opportunity to identify specific MHC I motifs in vitro.The combination of random peptide library,LC-MS/MS and De Novo Sequencing can be an important complement to the identification of MHC I motif.
ORGANISM(S): Sus scrofa domesticus (domestic pig) 
2021-09-09 | PXD019523 | Pride
Mhc class i，random peptide library，lc-ms/ms，de novo sequencing 
MetabolomicsTheabrownin from Pu-erh tea attenuates hypercholesterolemia via modulation of gut microbiota and bile acid metabolism
Pu-erh tea displays cholesterol-lowering properties, but the underlying mechanism has not been elucidated. Theabrownin is one of the most active and abundant pigments in Pu-erh tea. Here, we show that theabrownin alters the gut microbiota in mice and humans, predominantly suppressing microbes associ...
2021-11-18 | MTBLS1259 | MetaboLights
MetabolomicsAge-, sex- and proximal-distal-resolved multi-omics identifies regulators of intestinal aging in non-human primates.

The incidence of intestinal diseases increases with age, but the regulators of gut aging and the molecules linking gut aging and diseases remain largely unknown. By profiling the transcriptome, proteome, phosphoproteome and metabolome of 104 Macaca fascicularis large intestinal tissues, ...

2023-12-14 | MTBLS7612 | MetaboLights
MetabolomicsHyocholic acid species as novel biomarkers for metabolic disorders
Hyocholic acid (HCA) is a major bile acid (BA) species in the BA pool of pigs, a species known for its exceptional resistance to spontaneous development of diabetic phenotypes. HCA and its derivatives are also present in human blood and urine. We investigate whether human HCA profiles can predict th...
2021-10-06 | MTBLS2343 | MetaboLights
MetabolomicsIntegrated metabolomics and network pharmacology investigation of cardioprotective effects of myricetin after 1-week high-intensity exercise

Cardiovascular adverse effects caused by high-intensity exercise (HIE) have become a public health problem of widespread concern. As a phytochemical with potential therapeutic effects, the therapeutic effect and metabolic regulation mechanism of myricetin have rarely been studied. In this study, ...

2023-03-06 | MTBLS5608 | MetaboLights
UnknownInsights into the blood, gut, and oral microbiomes in Chinese patients with myocardial infarction: a case-control study.
Not available
S-EPMC12008866 | biostudies-literature
ProteomicsIntegrated transcriptomic and proteomic analysis reveals Runx2b-associated molecular regulation of intermuscular bone development in Culter alburnus
This dataset contains LC-MS/MS-based proteomic data generated from muscle/myoseptal tissues of wild-type, heterozygous runx2b mutant, and homozygous runx2b mutant Culter alburnus individuals. The study aimed to characterize proteomic changes associated with runx2b-mediated intermuscular bone reducti...
ORGANISM(S): Culter alburnus 
2026-09-07 | PXD080591 | Pride
Culter alburnus  intermuscular bone  runx2b  proteomics  dia  lc-ms/ms  gene editing  skeletal development  muscle/myoseptal tissue 
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