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MetabolomicsMetabolite signatures of diverse Camellia sinensis tea populations
Tea plants (Camellia sinensis) present an excellent system to study evolution and diversification of specialized metabolites due to their abundance in classes, numbers and contents. A large number of tea cultivars have been cultivated throughout the world not only because of their adaption to differ...
2020-10-05 | MTBLS1405 | MetaboLights
MetabolomicsMetabolomic approaches to dissect dysregulated metabolism in the progression of pre-diabetes to T2DM

Most of pre-diabetes were eventually progress to diabetes, thereby profiling of prediabetic metabolic disorders may be an effective targeted preventive measure. We aimed to elucidate internal motivation of the progression of pre-diabetes to type 2 diabetes mellitus (T2DM) from a metabolic perspec...

2024-04-29 | MTBLS8644 | MetaboLights
ProteomicsHuman serum samples proteomic analysis
Vitamin D deficiency affected the abnormal protein expression, resulting in the abnormal activation of complement system.
ORGANISM(S): Homo sapiens (Human) 
2023-03-11 | PXD036152 | Pride
Serum Proteomic Label-free Human 
UnknownTNFRSF13B Variant-Induced TACI Dysregulation Underlies CAEBV Pathogenesis.
Not available
S-EPMC12830494 | biostudies-literature
UnknownGenotype-Guided Dosing of Warfarin in Chinese Adults: A Multicenter Randomized Clinical Trial.
Not available
S-EPMC7439928 | biostudies-literature
ProteomicsAnalysis of protein expression changes in patients with prediabetes using high-throughput proteomics
Objective: This study aimed to explore the mechanisms of early-onset T2DM by analyzing proteomic changes at different stages of glucose metabolism. Methods: A total of 40 individuals undergoing routine physical health examinations between December 2016 and April 2017 were enrolled. Subjects were di...
ORGANISM(S): Homo Sapiens 
PXD035367 |
ProteomicsComprehensive proteomic profiling of aqueous humor in idiopathic uveitis and Vogt-Koyanagi-Harada syndrome
In this study, 44 AH samples were subjected to a quantitative analysis using SWATH, and 557 proteins were identified in each sample according to a well-established library of 634 proteins. Proteomic profiles in AH of IU and VKH groups were significantly different from normal controls, whereas relati...
ORGANISM(S): Homo Sapiens 
PXD041318 |
ProteomicsTargeted proteomic analysis of aqueous humor in idiopathic uveitis and Vogt-Koyanagi-Harada syndrome
Extreme gradient boosting (XGBoost), an efficient and robust machine learning algorithm, was used to develop a model for classifying the IU, VKH, and control groups. The three proteins deemed most important were transferrin (TF), calsyntenin-1 (CLSTN1), and retinol-binding protein 4 (RBP4), which re...
ORGANISM(S): Homo Sapiens 
PXD043575 |
ProteomicsProteomics reveals that immunoglobulin abnormalities and immune dysregulation in patients with post–COVID-19 condition
Vitamin D (VD) has a coordinated immune function. Decreased VD levels are closely related to the occurrence of post-COVID-19 Conditions (PCC), but the specific mechanism is still unclear. Methods: We collected 50 PCC patient serum samples and divided them into three groups by different VD levels: VD...
ORGANISM(S): Homo Sapiens 
2025-11-27 | PXD059686 |
ProteomicsProteomics analysis of three tea cultivars
To decipher phenotypic differences in flavonoid metabolism and the abundance of UGT enzymes involved in flavonol glycoside biosynthesis, an integrated proteomics and metabolomics analysis was conducted on three tea cultivars (Camellia sinensis), namely Jinfenghuang, Fuyun 6 and Bantianyao.
ORGANISM(S): Camellia Sinensis 
2024-01-30 | PXD048997 |
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