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Tea plants (Camellia sinensis) present an excellent system to study evolution and diversification of specialized metabolites due to their abundance in classes, numbers and contents. A large number of tea cultivars have been cultivated throughout the world not only because of their adaption to differ...
2020-10-05 | MTBLS1405 | MetaboLights

Most of pre-diabetes were eventually progress to diabetes, thereby profiling of prediabetic metabolic disorders may be an effective targeted preventive measure. We aimed to elucidate internal motivation of the progression of pre-diabetes to type 2 diabetes mellitus (T2DM) from a metabolic perspec...

2024-04-29 | MTBLS8644 | MetaboLights
Vitamin D deficiency affected the abnormal protein expression, resulting in the abnormal activation of complement system.
ORGANISM(S): Homo sapiens (Human) 
2023-03-11 | PXD036152 | Pride
Objective: This study aimed to explore the mechanisms of early-onset T2DM by analyzing proteomic changes at different stages of glucose metabolism. Methods: A total of 40 individuals undergoing routine physical health examinations between December 2016 and April 2017 were enrolled. Subjects were di...
ORGANISM(S): Homo Sapiens 
2022-10-19 | PXD035367 |
Extreme gradient boosting (XGBoost), an efficient and robust machine learning algorithm, was used to develop a model for classifying the IU, VKH, and control groups. The three proteins deemed most important were transferrin (TF), calsyntenin-1 (CLSTN1), and retinol-binding protein 4 (RBP4), which re...
ORGANISM(S): Homo Sapiens 
2023-07-06 | PXD043575 |
Vitamin D (VD) has a coordinated immune function. Decreased VD levels are closely related to the occurrence of post-COVID-19 Conditions (PCC), but the specific mechanism is still unclear. Methods: We collected 50 PCC patient serum samples and divided them into three groups by different VD levels: VD...
ORGANISM(S): Homo Sapiens 
2025-11-27 | PXD059686 |
To decipher phenotypic differences in flavonoid metabolism and the abundance of UGT enzymes involved in flavonol glycoside biosynthesis, an integrated proteomics and metabolomics analysis was conducted on three tea cultivars (Camellia sinensis), namely Jinfenghuang, Fuyun 6 and Bantianyao.
ORGANISM(S): Camellia Sinensis 
2024-01-30 | PXD048997 |
Background: MicroRNAs (miRNAs) are a class of single-stranded non-coding small RNAs (sRNAs) that are 20-24 nucleotides (nt) in length. Extensive studies have indicated that miRNAs play important roles in plant growth, development, and stress responses. With more copper (Cu) and copper-containing com...
ORGANISM(S): Vitis labrusca x Vitis vinifera 
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