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ProteomicsCocoon LC-MS/MS-Silkworm cultivation predating the Silk Road in southern Central Asia (2000 BCE)
We conducted proteomics analyses on three cocoons recovered from the Sapalli Tepe (approximately 2000 to 1500 BCE) site in Uzbekistan. This dataset contains LC-MS/MS data associated with the analysis of cocoons including Sapalli-C-1 (S1), Sapalli-C-2 (S2), Sapalli-C-3 (S3), Bombyx mori (S4), and Bom...
ORGANISM(S): Bombyx mori (Silk moth) 
2026-09-11 | PXD084037 | Pride
Cocoon Lc-ms/ms 
MetabolomicsAcupuncture Synergized With Bortezomib Improves Survival of Multiple Myeloma Mice via Decreasing Metabolic Ornithine
Multiple myeloma (MM) is a hematological malignancy worldwide in urgent need for novel therapeutic strategies. Since Velcade (bortezomib) was approved for the treatment of relapsed/refractory MM in 2003, we have seen considerable improvement in extending MM patient survival. However, most patients a...
2022-02-21 | MTBLS3487 | MetaboLights
ProteomicsUV‑ARTP compound mutagenesis breeding improves macrolactin production of Bacillus siamensis and reveals metabolism changes by proteomic
Macrolactin is a compound with complex macrolide structure which only be obtained through microbiological fermentation now. It has excellent antifungal, antibacterial and antitumor activity. In this study, Bacillus siamensis YB304 was used as the research object, and a mutant Mut-K53 with stable gen...
ORGANISM(S): Bacillus Siamensis 
PXD043264 |
ProteomicsThe origin and evolution of bioluminescence of fireflies
provide new perspectives and important resources for further exploring bioluminescence origin and evolution in insects
ORGANISM(S): Luciola Terminalis 
PXD015227 |
ProteomicsGenetic origin and evolution of bioluminescence of fireflies
provide new perspectives and important resources for further exploring bioluminescence origin and evolution in insects
ORGANISM(S): Lamprigera Yunnana 
PXD015226 |
ProteomicsSFXN2 adjusts cell proliferation in multiple myeloma
SFXN2 adjusts cell proliferation in multiple myeloma
ORGANISM(S): Homo Sapiens 
PXD027607 |
ProteomicsCD229 promotes multiple myeloma cell proliferation by regulating RAS/ERK pathway
Flag antibody was used for immunoprecipitation, and cd229-OE partial binding protein was searched by protein spectrum in CD229-OE multiple myeloma cell line, and its interaction was analyzed.
ORGANISM(S): Homo Sapiens 
2022-03-09 | PXD032177 |
ProteomicsBRAF inhibitors enhance erythropoiesis and treat anemia through paradoxical activation of MAPK
Erythropoiesis is a crucial part in hematopoietic system, while facing disruptions from various diseases conditions. Anemia and blood shortages has become global challenges, with current finite pharmacological options like EPO or glucocorticoids having limitations, especially in genetic anemias like...
ORGANISM(S): Homo Sapiens 
PXD055730 |
ProteomicsA novel variant of Salmonella enterica serovar Typhimurium with a rough colony morphology and multidrug resistance
Salmonella enterica serovar Typhimurium (S. Typhimurium) is a major cause of salmonellosis, with various multidrug-resistant pathovariants emerging. Here, we investigated a distinct rough colony variant with potentially enhanced environmental adaptation in China. Whole-genome sequencing of 2,212 Chi...
ORGANISM(S): Salmonella Enterica Subsp. Enterica Serovar Typhimurium Str. Lt2 
PXD047483 |
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