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Despite years of effort, exact pathogenesis of non-alcoholic fatty liver disease (NAFLD) remains obscure. To gain an insight into the regulatory roles of microRNAs (miRNAs) in aberrant energy metabolic status and pathogenesis of NAFLD, we analyzed the expression of miRNAs in livers of ob/ob mice, st...
ORGANISM(S): Mus musculus 
We determined the alkaloid content in Lycoris longituba, Lycoris incarnata, and Lycoris sprengeri, and performed a SWATH-MS-based quantitative approach to detect proteome changes in the three Lycoris.
ORGANISM(S): Amaryllidaceae 
2023-02-23 | PXD040341 |
Despite the crucial biological roles of arginine, its reactivity and ligandability in the human proteome are not well-explored. In this study, we employed the activity-based protein profiling approach using phenylglyoxal-based chemical probes to globally profile arginine residues. By screening a foc...
ORGANISM(S): Homo Sapiens 
2025-08-16 | PXD056202 |
we aimed to explore the molecular mechanism underlying its effects through blood proteomics and transcriptomics analyses. To achieve this, mice were orally administered BLX for 24 h after being treated with 5 mg/kg lipopolysaccharide (LPS). The results demonstrated that BLX effectively down-regulate...
ORGANISM(S): Mus Musculus 
2024-04-11 | PXD051353 |
DPSCs derivedgenerated from the three different donors were transfectedinfected with ETV2-overexpressing lentiviralrus particles or control lentiviralus particles. Protein samples were harvested after 10 days of endothelial differentiation. Proteome profiling was performed by the iProteome platform ...
ORGANISM(S): Homo Sapiens 
2020-03-21 | PXD018138 |
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