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ProteomicsPhosphoproteomic analysis of Staphylococcus aureus
S. aureus is one of the major human pathogens that greatly impacts individuals and causes a variety of illnesses ranging from minor skin infections to life-threatening diseases, such as endocarditis, pneumonia, septicemia and toxic shock syndrome. Stk1/Stp1 are particular important for S. aureus pat...
ORGANISM(S): Staphylococcus aureus 
2018-10-24 | PXD006285 | Pride
Phosphoproteomic Stp1 Stk1 Staphylococcus aureus 
ProteomicsPTMC_The proteomic profiles of pyridinium-based strategy for lysine-selective protein modification in live cells
A new bioorthogonal lysine-labeling strategy based on cationic-pyridinium activated ester, which renders the modification of peptides and proteins’ lysine residues with ultrafast kinetics and excellent specificity under aqueous solution, and profiled reactive-lysine proteome in vitro and in live cel...
ORGANISM(S): Homo Sapiens 
2023-10-24 | PXD036388 |
ProteomicsGlobal profiling of protein S-palmitoylation in the second-generation merozoites of Eimeria tenella
The intracellular protozoan Eimeria tenella is responsible for avian coccidiosis which is characterized by intestinal injury. During developmental cycle, E. tenella undergoes versatile transitional stages such as oocyst, sporozoites, merozoites as well as gametocytes. These developmental transitions...
ORGANISM(S): Eimeria Tenella 
2023-09-01 | PXD045061 |
ProteomicsHMGB2 promote ESCC tumorigenesis and predict neoadjuvant therapy response
Recent studies have demonstrated that chronic stress can enhance the development of multiple human diseases, including cancer. However, the role of chronic stress in esophageal carcinogenesis and its underlying molecular mechanisms remain unclear. This study uncovered that dysregulated cholesterol m...
ORGANISM(S): Mus Musculus 
2025-01-09 | PXD059616 |
ProteomicsChronic stress-induced cholesterol metabolism abnormalities promote ESCC tumorigenesis and predict neoadjuvant therapy response
chronic stress activates the GCR-HMGB2-LDLR axis via cortisol release, leading to abnormal cholesterol metabolism and ultimately promoting esophageal carcinogenesis
ORGANISM(S): Homo Sapiens 
2025-01-09 | PXD059578 |
ProteomicsProteomics analysis report of esophageal squamous cell carcinoma treated by Dasabuvir
In order to detect the effect of Dasabuvir on the protein expression of esophageal cancer cells, we used control and drug-added KYSE150 cells for proteomic analysis
ORGANISM(S): Homo Sapiens 
2022-01-24 | PXD031186 |
ProteomicsTraceless peptide and protein modification via rational tuning of halopyridiniums
Building on the insights gained from systematically investigating of aromatic nucleophilic substitution (SNAr) and thiol-exchange, we identified the highly electron-deficient halopyridiniums as a tunable and predictable reaction platform for adjusting electrophilicity and thiol-cleavability by follo...
ORGANISM(S): Homo Sapiens 
2023-09-25 | PXD045683 |
ProteomicsProteomics of two different cold tolerance winter rapeseed cultivars
Leaf proteomics of two different cold tolerance winter rapeseed cultivars under cold stress
ORGANISM(S): Brassica Napus Var. Napus 
2021-04-24 | PXD023323 |
ProteomicsPTMC_A pyridinium-based strategy for bioorthogonal conjugation-assisted purification method for profiling cell surface proteome
Cell surface proteins (CSPs) are valuable targets for therapeutic agents, but achieving highly selective CSP enrichment in cellular physiology remains a technical challenge. To address this challenge, we propose a newly developed sulfo-pyridinium-ester (SPE) cross-linking probe, followed by two-step...
ORGANISM(S): Homo Sapiens 
2023-08-11 | PXD044541 |
ProteomicsProteomics analysis report of esophageal squamous cell carcinoma treated by Arbidol
In order to detect the effect of Arbidol on the protein expression of esophageal cancer cells, we used control and drug-added KYSE150 cells for proteomic analysis
ORGANISM(S): Homo Sapiens 
2022-06-27 | PXD034944 |
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