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ProteomicsIdentification of proteolytic fragments of human hemoglobin
The uploaded data is related to the identification of the antibacterial/antiviral human peptide HBB 12-147 in hemoglobin digestion with Napsin-A
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2020-12-15 | MSV000086600 | MassIVE
ProteomicsDefining HLA-II ligand processing and binding rules with mass spectrometry enhances cancer epitope prediction
Increasing evidence indicates CD4+ T cells can recognize cancer-specific antigens and control tumor growth. However, it remains difficult to predict the antigens that will be presented by human leukocyte antigen class II molecules (HLA-II) - hindering efforts to optimally target them therapeutically...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2019-06-18 | MSV000083991 | MassIVE
TranscriptomicsTranscriptional signature of progesterone-induced germinal vesicle breakdown in the fathead minnow ovary (Pimephales promelas)
A growing number of studies have examined transcriptional responses to sex steroids along the hypothalamic-pituitary-gonadal axis in teleost fishes. However, data is are lacking on the molecular signaling cascades that underlie progesterone signaling. The objectives of the present study were to ch...
ORGANISM(S): Pimephales promelas 
2013-07-19 | E-GEOD-43601 | biostudies-arrayexpress
TranscriptomicsUsing transcriptomic tools to evaluate biological effects across effluent gradients at a diverse set of study sites in Minnesota, USA
To assess the impact of a municiple effluent across different environments, a gradient design (upstream, downstream, and at effluent) was set up across three waste water treatment plant outflows in three different regions of MN. These three sites represents vastly different land use and contaminati...
ORGANISM(S): Pimephales promelas 
2013-12-13 | E-GEOD-53204 | biostudies-arrayexpress
TranscriptomicsIntegrated approach to explore the mechanisms of aromatase inhibition and recovery on fathead minnow ovaries
Aromatase, a member of the cytochrome P450 superfamily, is a key enzyme in estrogen synthesis and is responsible for the aromatization of androgens into estrogens. Here, we used an integrated approach to better understand the effects of aromatase inhibition as well as the mechanisms involved in the ...
ORGANISM(S): Pimephales promelas 
2013-11-01 | E-GEOD-51961 | biostudies-arrayexpress
TranscriptomicsExpression profiling of mmi1 delta cells, using tiling microarray in S. pombe
We used tiling microarrays to identify up-regulated genes in mmi1 delta cells. Because these cells grow very poorly due to misexpression of mei4 gene, we combined mmi1 delta mutation to a partial deletion of mei4. Cells carrying only mei4 partial deletion were also analyzed in our transcriptomics to...
ORGANISM(S): Schizosaccharomyces pombe 
2012-08-31 | E-GEOD-31119 | biostudies-arrayexpress
UnknownUpdate on the third international stroke trial (IST-3) of thrombolysis for acute ischaemic stroke and baseline features of the 3035 patients recruited.
Not available
S-EPMC3286387 | biostudies-literature
UnknownThe benefits and harms of intravenous thrombolysis with recombinant tissue plasminogen activator within 6 h of acute ischaemic stroke (the third international stroke trial [IST-3]): a randomised controlled trial.
Not available
S-EPMC3386495 | biostudies-literature
UnknownEffect of alteplase on the CT hyperdense artery sign and outcome after ischemic stroke.
Not available
S-EPMC4731690 | biostudies-literature
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