Sort   by:  
 Page size 
GenomicsTargeted sequencing CYLD cutaneous syndrome
Patients with CYLD cutaneous syndrome (CCS; syn. Brooke-Spiegler syndrome) carry germline mutations in the tumor suppressor CYLD and develop multiple skin tumors with diverse histophenotypes. We comprehensively profiled the genomic landscape of 42 benign and malignant tumors across 13 individuals fr...
EGAS00001003840 | EGA
GenomicsMethylation CYLD cutaneous syndrome
Patients with CYLD cutaneous syndrome (CCS; syn. Brooke-Spiegler syndrome) carry germline mutations in the tumor suppressor CYLD and develop multiple skin tumors with diverse histophenotypes. We comprehensively profiled the genomic landscape of 42 benign and malignant tumors across 13 individuals fr...
EGAS00001003800 | EGA
GenomicsRNA sequencing CYLD cutaneous syndrome
Patients with CYLD cutaneous syndrome (CCS; syn. Brooke-Spiegler syndrome) carry germline mutations in the tumor suppressor CYLD and develop multiple skin tumors with diverse histophenotypes. We comprehensively profiled the genomic landscape of 42 benign and malignant tumors across 13 individuals fr...
EGAS00001003841 | EGA
GenomicsWhole exome sequencing CYLD cutaneous syndrome
Patients with CYLD cutaneous syndrome (CCS; syn. Brooke-Spiegler syndrome) carry germline mutations in the tumor suppressor CYLD and develop multiple skin tumors with diverse histophenotypes. We comprehensively profiled the genomic landscape of 42 benign and malignant tumors across 13 individuals fr...
EGAS00001003839 | EGA
UnknownJust the facts: What drugs are safe and effective for COVID-19?
Not available
S-EPMC7267102 | biostudies-literature
GenomicsComprehensive nucleosome mapping of the human genome in cancer progression
Altered chromatin structure is a hallmark of cancer, and inappropriate regulation of chromatin structure may represent the origin of transformation. Several important studies have mapped human nucleosome distributions genome wide, but the genome-wide role of chromatin structure in cancer progression...
ORGANISM(S): Homo sapiens 
2015-10-27 | E-GEOD-74340 | biostudies-arrayexpress
TranscriptomicsRNA-seq of human intestinal organoids colonized with E. coli and other immature intestinal tissues
We performed RNA-seq to demonstrate that the epithelium of human pluripotent stem cell-derived human intestinal organoids is globally similar to the immature human epithelium and we utilize HIOs to investigate complex host-microbe interactions in this naive epithelium. RNA was isolated using the mir...
ORGANISM(S): Homo sapiens 
2017-09-01 | E-MTAB-5801 | biostudies-arrayexpress
TranscriptomicsRNA expression data from glomeruli lacking von Hippel-Lindau protein in podocytes
We and others have previously shown that glomerular endothelial cells and podocytes express hypoxia-inducible transcription factors (HIFs). HIFs bind to hypoxia response elements in target genes, such as vascular endothelial growth factor, which is continually produced by podocytes throughout life....
ORGANISM(S): Mus musculus 
2010-08-03 | E-GEOD-20235 | biostudies-arrayexpress
TranscriptomicsGenome-wide analysis of Estrogen Receptor-mediated response to acute Estradiol treatment in liver (expression)
Estrogen-based treatments have numerous extra-reproductive effects. On the one hand, they have protective metabolic actions against abdominal fat accumulation, type 2 diabetes, liver steatosis,… But, on the other hand, the oral route of administration, presumably due to a hepatic impact on liver-d...
ORGANISM(S): Mus musculus 
2016-05-13 | E-GEOD-70329 | biostudies-arrayexpress
TranscriptomicsRNA-seq of human intestinal organoids infected with Salmonella enterica at 2.5h and 8h post infection
The purpose of this experiment was to identify intestinal epithelial responses to various strains of Salmonella enterica. Human intestinal organoids were infected with three serovars of Salmonella; Typhimurium, Enteritidis and Typhi, as well as type 3 secretion system -1 and -2 mutants in Typhimuriu...
ORGANISM(S): Homo sapiens 
2021-10-01 | E-MTAB-10451 | biostudies-arrayexpress
Sort   by:  
 Page size