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GenomicsBreast Cancer Suppressor Role of RUNX1: Estrogen-dependent Regulation of AXIN1 and b-catenin
The transcription factor RUNX1 exhibits recurrent loss-of-function mutations in estrogen receptor-positive (ER+) breast cancer (BCa). Its knockdown in vitro decreased AXIN1 expression in estrogen-dependent manner. Consistently, RUNX1 and AXIN1 mRNA levels are strongly correlated in ER+, not ER- tu...
ORGANISM(S): Homo sapiens 
2016-02-22 | E-GEOD-65313 | biostudies-arrayexpress
TranscriptomicsHeparin promotes cardiac differentiation of human pluripotent stem cells in chemically defined albumin-free medium enabling consistent manufacture of cardiomyocytes
Cardiomyocytes can be differentiated from human pluripotent stem cells (hPSCs) in defined conditions, but efficient and consistent cardiomyocyte differentiation often requires expensive reagents such as B27 supplement or recombinant albumin. Using a chemically defined albumin-free (E8 basal) medium,...
ORGANISM(S): Homo sapiens 
2016-07-28 | E-GEOD-81711 | biostudies-arrayexpress
UnknownHistone modifications and Sp1 promote GPR160 expression in bone cancer pain within rodent models
Not available
S-SCDT-10_1038-S44319-024-00292-6 | biostudies-other
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