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TranscriptomicsExpression data from the starved first larval stage (L1) C. elegans animals that were incubated in S-basal buffer for 30 hours after bleaching
How animals coordinate gene expression in response to starvation is an outstanding problem closely linked to aging, obesity, and cancer. Newly hatched Caenorhabditis elegans respond to food deprivation by halting development and promoting long-term survival (L1 diapause), thereby providing an excell...
ORGANISM(S): Caenorhabditis elegans 
2014-05-16 | E-GEOD-45651 | biostudies-arrayexpress
TranscriptomicsExposure of C. elegans to AOBr-containing surface water samples and to a M. aeruginosa batch culture
Elevated levels of adsorbable organic bromine compounds (AOBr) have been detected in German lakes, and cyanobacteria like Microcystis, which are known for the synthesis of microcystins, are one of the main producers of natural organobromines. However, very little is known about how environmental rea...
ORGANISM(S): Caenorhabditis elegans 
2015-05-12 | E-GEOD-68709 | biostudies-arrayexpress
TranscriptomicsComparison of transcriptome of in vitro and in vivo-produced bovine fetuses; specifically in liver and placental tissues.
During the past several decades, in vitro fertilization (IVF) has been increasingly used both in animal production and human infertility treatment. Animals derived from in vitro manipulation are occasionally associated with abnormal offspring syndrome (AOS) and other developmental abnormalities. By ...
ORGANISM(S): Bos taurus 
2011-07-25 | E-GEOD-29987 | biostudies-arrayexpress
TranscriptomicsTranscription profiling time series of a human conjunctival epithelial cell line treated with retinoic acid
Purpose. How vitamin A contributes to the maintenance of the wet-surfaced phenotype at the ocular surface is not well understood. We sought to identify vitamin A responsive genes in ocular surface epithelia using gene microarray analysis of cultures of a human conjunctival epithelial cell line (HCjE...
ORGANISM(S): Homo sapiens 
2007-12-12 | E-GEOD-2835 | biostudies-arrayexpress
TranscriptomicsMucosal responses of healthy humans to three different probiotic Lactobacillus bacteria
Probiotic bacteria, specific representatives of bacterial species that are a common part of the human microbiota, are proposed to deliver health benefits to the consumer by modulation of intestinal function via largely unknown molecular mechanisms. To explore in vivo mucosal responses of healthy adu...
ORGANISM(S): Homo sapiens 
2010-09-08 | E-GEOD-18741 | biostudies-arrayexpress
TranscriptomicsDevelopmental profiling of spiral ganglion neurons reveals insights into auditory circuit assembly
The sense of hearing depends on the faithful transmission of sound information from the ear to the brain by spiral ganglion (SG) neurons. However, how SG neurons develop the connections and properties that underlie auditory processing is largely unknown. We catalogued gene expression in mouse SG ne...
ORGANISM(S): Mus musculus 
2011-07-14 | E-GEOD-29766 | biostudies-arrayexpress
GenomicsA novel phosphate-starvation response in fission yeast requires the endocytic function of Myosin I (ChIP-seq)
S. pombe Myosin I (MyoI) plays a key role in cytoskeletal functions, in particular it is part of the endocytotic machinery. Here we show a novel role for MyoI in regulating the response to low phosphate stress. Deletion of MyoI led to an increased proliferation in low phosphate media when compared t...
ORGANISM(S): Schizosaccharomyces pombe 
2015-09-15 | E-GEOD-67105 | biostudies-arrayexpress
TranscriptomicsGenome-wide expression profiling of Drosophila adult heart organogenesis
The abstract of the manuscript titled "Signalling pathways involved in adult heart formation revealed by gene expression profiling in Drosophila" is given below: "Drosophila provides a powerful system for defining the complex genetic programs that drive organogenesis. Under control of...
ORGANISM(S): Drosophila melanogaster 
2007-08-28 | E-GEOD-7689 | biostudies-arrayexpress
TranscriptomicsA novel phosphate-starvation response in fission yeast requires the endocytic function of Myosin I (RNA-seq)
S. pombe Myosin I (MyoI) plays a key role in cytoskeletal functions, in particular it is part of the endocytotic machinery. Here we show a novel role for MyoI in regulating the response to low phosphate stress. Deletion of MyoI led to an increased proliferation in low phosphate media when compared t...
ORGANISM(S): Schizosaccharomyces pombe 
2015-09-15 | E-GEOD-65579 | biostudies-arrayexpress
TranscriptomicsTranscriptomics of circulating human eosinophils
Global expression pattern in eosinophils in various conditions such as eosinophilic asthma, hypereosinophilic dermatological diseases, parasitosis and pulmonary aspergillosis. Eosinophil were isolated from peripheral blood by FACS from 4 hypereosinophilic conditions: eosinophilic asthma (4 replicate...
ORGANISM(S): Homo sapiens 
2015-12-10 | E-GEOD-65239 | biostudies-arrayexpress
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