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TranscriptomicsWithaferin A (WA) causes cell death in prostate cells.
Withaferin A (WA), a major chemical component of an Indian herb Withania somnifera, induces cell death (apoptosis/necrosis) in a variety of tumor cells, but its molecular mechanism remains elusive. We report that WA induces cell death selectively in high-grade prostate (PC-3 and DU-145) and tongue (...
ORGANISM(S): Homo sapiens 
2015-08-02 | E-GEOD-55728 | biostudies-arrayexpress
TranscriptomicsA Highly Sensitive and Unbiased Approach for Elucidating Antibody Repertoires
Developing B lymphocytes undergo V(D)J recombination to assemble germline V, D, and J gene segments into exons that encode the antigen-binding variable region of immunoglobulin (Ig) heavy (H) and light (L) chains. IgH and IgL chains associate to form the B cell receptor (BCR), which upon antigen bi...
ORGANISM(S): Mus musculus 
2016-07-22 | E-GEOD-82126 | biostudies-arrayexpress
TranscriptomicsGenome-wide expression profiling of the response to D-limonene in Saccharomyces cerevisiae
Metabolic engineering of Saccharomyces cerevisiae for efficient monoterpenes production was mostly restricted by the limited tolerance to these chemicals. Understanding of the molecular mechanisms underlying the tolerance of S. cerevisiae to monoterpenes was essential for the de novo biosynthesis th...
ORGANISM(S): Saccharomyces cerevisiae 
2013-12-23 | E-GEOD-34665 | biostudies-arrayexpress
UnknownATP-citrate lyase is an epigenetic regulator to promote obesity-related kidney injury.
Not available
S-EPMC6662982 | biostudies-literature
TranscriptomicsGene expression data from liver of rat fed a high-fat diet and high-fructose water without/with Eucommia ulmoides leaves
To investigate effects of intake of Eucommia ulmoides leaves on hyperlipidemia, we performed gene expression profiling on rat liver by microarray analysis. Microarray analysis revealed that Eucommia ulmoides leaves up-regulated the gene expression involved in alpha-, beta-, and omega-oxidation of fa...
ORGANISM(S): Rattus norvegicus 
2011-08-21 | E-GEOD-24377 | biostudies-arrayexpress
MetabolomicsFlavonoid Biosynthesis Is Likely More Susceptible to Elevation and Tree Age Than Other Branch Pathways Involved in Phenylpropanoid Biosynthesis in Ginkgo Leaves
Ginkgo leaves are always resources for flavonoids pharmaceutical industry. However, the effect of the elevation and tree age changes on flavonoid biosynthesis have not been detailly explored in Ginkgo leaves. In addition, whether these environmental pressures have similar effects on the biosynthesis...
2020-12-14 | MTBLS962 | MetaboLights
UnknownElectroacupuncture at Guanyuan (CV 4), Zusanli (ST 36) and Baihui (DU 20) regulate the aging-related changes in gene expression profile of the hippocampus in sub-acutely aging rats.
Not available
S-EPMC5774823 | biostudies-literature
Unknownd-Orbital steered active sites through ligand editing on heterometal imidazole frameworks for rechargeable zinc-air battery.
Not available
S-EPMC7673988 | biostudies-literature
UnknownRole of mTOR through Autophagy in Esophageal Cancer Stemness.
Not available
S-EPMC9040713 | biostudies-literature
UnknownLymph node characteristics of 6279 N1 differentiated thyroid cancer patients.
Not available
S-EPMC7040862 | biostudies-literature
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