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TranscriptomicsThe tumor suppressor Rassf1a prevents mouse liver tumorigenesis and regulates levels of the oncogenic kinase Tbk1 and of beta tubulin gene expression in the liver
The tumor suppressor gene RASSF1A (Ras association domain family protein 1A) coding for a microtubule stabilizing protein is epigenetically silenced in most human cancers. As a binding partner of the kinases MST1 and MST2, the mammalian orthologues of the Drosophila Hippo kinase, RASSF1A is a potent...
ORGANISM(S): Mus musculus 
2016-05-31 | E-GEOD-73911 | biostudies-arrayexpress
UnknownFunctional differentiation and genetic diversity of rice cation exchanger (CAX) genes and their potential use in rice improvement.
Not available
S-EPMC11018787 | biostudies-literature
TranscriptomicsBaseline expression of symptomatic and asymptomatic subjects after YF17D vaccination in Trial 2
This study investigates how the baseline expression level of genes impact symptomatic outcome of flaviviral infection. Before given the YF17D vaccine, whole blood was extracted into tempus tubes from vaccinated subjects. Thereafter, the subjects were assessed if they experienced adverse events (or s...
ORGANISM(S): Homo sapiens 
2019-05-11 | E-MTAB-7931 | biostudies-arrayexpress
TranscriptomicsBaseline expression of symptomatic and asymptomatic subjects after YF17D vaccination in Trial 1
This study investigates how the baseline expression level of genes impact symptomatic outcome of flaviviral infection. Before given the YF17D vaccine, whole blood was extracted into tempus tubes from vaccinated subjects. Thereafter, the subjects were assessed if they experienced adverse events (or s...
ORGANISM(S): Homo sapiens 
2019-05-11 | E-MTAB-7928 | biostudies-arrayexpress
ModelsColitis-associated colon cancer
This model looks at the development of colitis-associated colon cancer in order investigate the mechanism behind inflammation-associated tumorigenesis. Dynamic simulations reveal that P53, MDM2, and AKT may constitute a core network responsible for the malignant transformation of colon epithelial ce...
4601 | Cell Collective
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