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TranscriptomicsTranscriptome comparison of human Extra-thymic AIRE expressing cells to medullary thymic epithelial cells and conventional antigen presenting dendritic cells.
The provenance of eTACs is unknown, and their characterisation in humans is currently absent. Using bulk RNA sequencing we compare the endogenous expression capacity for self-antigens between eTACs, mTECs and cDCs.
ORGANISM(S): Homo sapiens 
2019-01-14 | E-MTAB-7383 | biostudies-arrayexpress
TranscriptomicsSingle-cell RNA-sequencing of mouse thymic epithelial cells across the first year of life
The thymus shapes the T cell receptor repertoire, and is one of the first organs to rapidly age, with gross changes in cellularity and architecture. To resolve the nature of these changes we used SMART-Seq2 on FACS purified thymic epithelial cells (TEC) across the first year of mouse life. We sorted...
ORGANISM(S): Mus musculus 
2020-09-14 | E-MTAB-8560 | biostudies-arrayexpress
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