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TranscriptomicsR-loops are marks for histone H3 Ser10 phosphorylation and chromatin compaction
R-loops are transcription by-products that may constitute a threat to genome integrity. In addition to specific enzymes to remove them, eukaryotes rely on a number of mRNP biogenesis factors such as the THO complex, to prevent co-transcriptional R-loop formation. We show in Saccharomyces cerevisiae ...
ORGANISM(S): Saccharomyces cerevisiae 
2013-11-13 | E-GEOD-46627 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Arabidopsis wild type and hfr1/sics1 knock-out mutant seedlings exposed to low R/FR light
Aim of the experiment is the identification of genes differentially regulated in hfr1/sics1 seedlings relative to wild type after prolonged exposure to low R/FR. To this end, gene expression changes were analysed in Arabidopsis wild-type and hfr1/sics1 knock-out mutant seedlings exposed to low R/FR ...
ORGANISM(S): Arabidopsis thaliana 
2006-03-01 | E-MEXP-444 | biostudies-arrayexpress
TranscriptomicsscRNA-seq of human fetal lung explants with R-SPONDIN Inhibition and human fetal lung primary tissue
Here, we used single cell RNA-sequencing (scRNA-seq) to profile 13-week post-conception distal human fetal lung explants cultured in an air liquid interface system and treated with an LGR5 ectodomain adenovirus that inhibits R-Spondin function or control adenovirus. A third, non-infected, condition ...
ORGANISM(S): Homo sapiens 
2022-01-01 | E-MTAB-10662 | biostudies-arrayexpress
GenomicsAscl2 acts as an R-spondin/Wnt responsive switch to control stemness in intestinal crypts [ChIP-seq]
Wnt signals control three functions of intestinal crypts: maintenance of Lgr5 stem cells, proliferation of transit-amplifying daughters and formation of Paneth cells. Here, we study how the Wnt effector β-catenin/Tcf4 cooperates with the Wnt-activated transcription factor Ascl2 to control a stem ce...
ORGANISM(S): Homo sapiens 
2016-07-15 | E-GEOD-84456 | biostudies-arrayexpress
TranscriptomicsR. conorii transcriptional response within inoculation eschar battlefield
Rickettsia conorii, the causative agent of the MSF is transmitted to humans by the bite of infected ticks Rhipicephalus sanguineus. The skin thus constitutes an important barrier for the entry and propagation of R. conorii. Given this, analysis of the survival strategies used by the bacterium within...
ORGANISM(S): Rickettsia conorii 
2008-11-06 | E-GEOD-12130 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Arabidopsis thaliana seedlings after exposure to low R/FR light for a short and a long period of time
Aim of the experiment is the identification of regulatory genes rapidly induced by low R/FR and still up-regulated after prolonged exposure to FR-rich light. To this end, gene expression changes were analysed in Arabidopsis thaliana seedlings after exposure to low R/FR light for a short and a long p...
ORGANISM(S): Arabidopsis thaliana 
2006-03-01 | E-MEXP-443 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of genetically cerebral malaria-resistant (CM-R) and cerebral malaria-susceptible (CM-S) mouse strains
Gene expression patterns were investigated in well-defined genetically cerebral malaria-resistant (CM-R) and cerebral malaria-susceptible (CM-S) mouse strains. cDNA microarrays were used to search for differentially expressed genes in mouse brain. Four mouse strains, known to differ in susceptibilit...
ORGANISM(S): Mus musculus 
2005-06-30 | E-MEXP-370 | biostudies-arrayexpress
UnknownEfficicent (R)-phenylethanol production with enantioselectivity-alerted (S)-carbonyl reductase II and NADPH regeneration.
Not available
S-EPMC3866161 | biostudies-literature
TranscriptomicsThe transcriptional profilling of the thermosensitive self-incompatible het-R het-V strain undergoing cell death by incompatibility
In the filamentous fungus Podospora anserina, cell death by incompatibility can be monitored using the conditional self-incompatible (SI) het-R het-V strain. SI strains are homokaryotic strains bearing incompatible het genes in all nuclei. The co-expression of these het genes triggers cell death in ...
ORGANISM(S): Podospora anserina 
2013-01-01 | E-GEOD-21659 | biostudies-arrayexpress
TranscriptomicsRNA-seq of RNase R treated poly(A)-/ribo- RNAs from H9 cells
We have used RNA-seq to examine circular RNAs from RNase R treated poly(A)-/ribo- RNAs in human embryonic stem cells Examine circular RNAs in human embryonic stem cells
ORGANISM(S): Homo sapiens 
2013-06-18 | E-GEOD-48003 | biostudies-arrayexpress
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