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TranscriptomicsTranscription profiling of Stratagene human universal reference RNA labelled with different labelling protocols to test labelling protocols
Considerable variation in gene expression data from different DNA microarray platforms has been demonstrated. However, no characterization of the source of variation arising from labeling protocols has been performed. To analyze the variation associated with T7-based RNA amplification/labeling metho...
ORGANISM(S): Homo sapiens 
2007-07-24 | E-GEOD-3254 | biostudies-arrayexpress
ProteomicsInvestigating the Quantitative Proteomics of TMT Phosphorylation in Ningxia Wolfberry under Diverse Concentrations of Salt Stress: Unveiling Molecular Mechanisms and Implications
The experimental results revealed 2727 phosphorylated proteins, 5258 phosphorylated peptides and 5096 phosphorylation sites, which included 5252 quantifiable phosphorylated peptides and 5091 quantifiable phosphorylation sites on 2725 quantifiable modified proteins
ORGANISM(S): Lycium Barbarum 
2024-12-10 | PXD058720 |
TranscriptomicsTranscription profiling of human normal prostate tissue free of any pathological alteration
Prostate cancer is characterized by heterogeneity in the clinical course that often does not to correlate with morphologic features of the tumor. Metastasis reflects the most adverse outcome of prostate cancer, and to date there are no reliable morphologic features or serum biomarkers that can relia...
ORGANISM(S): Homo sapiens 
2008-06-15 | E-GEOD-6604 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human primary prostate tumor
Prostate cancer is characterized by heterogeneity in the clinical course that often does not to correlate with morphologic features of the tumor. Metastasis reflects the most adverse outcome of prostate cancer, and to date there are no reliable morphologic features or serum biomarkers that can relia...
ORGANISM(S): Homo sapiens 
2008-06-15 | E-GEOD-6606 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human normal prostate tissue adjacent to tumor
Prostate cancer is characterized by heterogeneity in the clinical course that often does not to correlate with morphologic features of the tumor. Metastasis reflects the most adverse outcome of prostate cancer, and to date there are no reliable morphologic features or serum biomarkers that can relia...
ORGANISM(S): Homo sapiens 
2008-06-15 | E-GEOD-6608 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human metastatic prostate tumor
Prostate cancer is characterized by heterogeneity in the clinical course that often does not to correlate with morphologic features of the tumor. Metastasis reflects the most adverse outcome of prostate cancer, and to date there are no reliable morphologic features or serum biomarkers that can relia...
ORGANISM(S): Homo sapiens 
2008-06-15 | E-GEOD-6605 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human prostate samples from normal donors and prostate cancer patients
This SuperSeries is composed of the following subset Series:; GSE6604: Expression data from Normal Prostate Tissue free of any pathological alteration; GSE6605: Expression data from Metastatic Prostate Tumor; GSE6606: Expression data from Primary Prostate Tumor; GSE6608: Expression data from Normal ...
ORGANISM(S): Homo sapiens 
2008-04-06 | E-GEOD-6919 | biostudies-arrayexpress
MetabolomicsProfiling the metabolome of uterine fluid for early detection of ovarian cancer

Ovarian cancer (OC) causes high mortality in women because of ineffective biomarkers for early diagnosis. Here, we perform metabolomics analysis on an initial training set of uterine fluid from 96 gynecological patients. A seven-metabolite-marker panel consisting of vanillylmandelic acid, norepin...

2023-03-06 | MTBLS4861 | MetaboLights
TranscriptomicsCytosolic splice isoform of Hsp70 nucleotide exchange factor Fes1 is required for the degradation of misfolded proteins in yeast
Cells maintain proteostasis by selectively recognizing and targeting misfolded proteins for degradation. In Saccharomyces cerevisiae, the Hsp70 nucleotide exchange factor Fes1 is essential for the degradation of chaperone-associated misfolded proteins by the ubiquitin-proteasome system. Here we show...
ORGANISM(S): Saccharomyces cerevisiae 
2016-02-29 | E-GEOD-78136 | biostudies-arrayexpress
GenomicsA PTIP-PA1 subcomplex promotes transcription for IgH class-switching independently from the associated MLL3/MLL4 methyltransferase complex
Class-switch recombination (CSR) diversifies antibodies for productive immune responses while maintaining stability of the B cell genome. Transcription at the immunoglobulin heavy-chain (Igh) locus targets CSRassociated DNA damage and is promoted by the BRCT domain-containing PTIP protein. Although ...
ORGANISM(S): Mus musculus 
2015-12-12 | E-GEOD-75930 | biostudies-arrayexpress
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