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ProteomicsLC-MS/MS identification of BMAL1 interaction proteins
Advances in circadian research revealed an intricate relationship between aging and circadian rhythms. However, whether and how the circadian machinery contribute to stem cell aging, especially in primates, remains poorly understood. In this study, we investigated the role of BMAL1, the only non-red...
ORGANISM(S): Homo sapiens (Human) 
2022-03-18 | PXD030570 | Pride
Bmal1 aging 
ProteomicsSelective killing of cancer cells by a small molecule targeting the stress response to ROS
Raj L, Ide T, Gurkar AU, Foley M, Schenone M, Li X, Tolliday NJ, Golub TR, Carr SA, Shamji AF, Stern AM, Mandinova A, Schreiber SL, Lee SW. Nature. 2011 475:231-4. doi: 10.1038/nature10167. PMCID: PMC3316487
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2014-01-27 | MSV000078537 | MassIVE
MetabolomicsDistinct succinate modifying products are clinically diagnostic and prognostic biomarkers for fumarate hydratase deficient renal cell carcinoma

Germline or somatic loss-of-function of fumarate hydratase (FH) predisposes patients to an aggressive form of renal cell carcinoma (RCC). Since other than tumor resection, there is no effective therapy for FH-deficient RCC, a competent method for early diagnosis and for early detection of recurre...

2022-08-12 | MTBLS3628 | MetaboLights
ProteomicsA comprehensive landscape of human organ N-glycoproteome
N-glycosylation, as a common post-translational modification with enormous structures, plays key roles in protein folding, cellular recognition and signaling pathways. State-of-the-art mass spectrometry-based N-glycoproteomics has enabled deep N-glycoproteome characterization of various human organs...
ORGANISM(S): Homo sapiens (Human) 
2026-05-13 | PXD070547 | Pride
Tissue Human N-glycosylation Profile 
ProteomicsMyo19 Interacting Proteins IP-MS
This project is aimed to detect the interacting proteins of mitochondria-tageting actin motor Myo19.
ORGANISM(S): Homo sapiens (Human) 
2022-06-09 | PXD033198 | Pride
Myo19 ip-ms 
TranscriptomicsChromatin immunoprecipitation of human cell lines with oestrogen receptor (ER), the E2F transcription factor 4 (E2F4),
The Goal of the experiment was to validate the predicted regulatory modules identified by an algorithm.For this we took advantage of the the genome-wide location analysis technique (or ?ChIP/chip?). We selected modules predicted to be bound by the estrogen receptor (ER), the E2F transcription factor...
ORGANISM(S): Homo sapiens 
2006-05-01 | E-MEXP-471 | biostudies-arrayexpress
ProteomicsCRISPR-Assisted Detection of RNA-Protein Interactions in Living Cells
We develop a CRISPR-Assisted RNA-Protein Interaction Detection method (CARPID), which leverages CRISPR/CasRx-based RNA targeting and proximity labeling to identify binding proteins of specific lncRNA in the native cellular context.
ORGANISM(S): Homo Sapiens 
2020-05-20 | PXD015702 |
ProteomicsParagorgia papillata and Chrysogorgia sp. skeletal proteome
This project contains raw bone proteome data for Paragorgia papillata and Chrysogorgia sp.
ORGANISM(S): Octocorallia 
2024-10-19 | PXD056993 |
ProteomicsProteome dataset of goat adipose-derived stem cells (gADSCs)
Proteome data derive from three different types of cells （uninfected gADSCs, gADSCs infected with the empty lentiviral vector, and gADSCs infected with the miR-204-5p lentiviral vector).
ORGANISM(S): Capra Hircus 
2023-06-29 | PXD043379 |
ProteomicsAffinity peptide ligands: New tools for chasing non-canonical N-phosphoproteome
Protein N-phosphorylation enrichment is faced with great difficulties due to the intrinsic instability of the N-P bond, which has seriously hindered its biological function unraveling. Current methods for N-phosphopeptides enrichment are challenging to fulfil high selectivity for all types of N-phos...
ORGANISM(S): Homo Sapiens Escherichia Coli Mus Musculus 
2024-12-12 | PXD058797 |
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