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TranscriptomicsProfiling the target genes for ZIP repressor in MCF-7
Using ChIP-DSL technology from Aviva Systems Biology to find out the whole genome targets for ZIP transcription repressor We analyzed arrays using specific ZIP antibody and negative control to acquire the enriched ratio of each gene
ORGANISM(S): Homo sapiens 
2010-05-06 | E-GEOD-13905 | biostudies-arrayexpress
TranscriptomicsProfiling the target genes for LSD1, MTA1, MTA2, and MTA3 in MCF-7
Using ChIP-DSL technology from AVIVA SYSTEMS BIOLOGY to find out the whole genome targets for LSD1, MTA1, MTA2, and MTA3 We analyzed arrays using antibodies against LSD1, MTA1, MTA2, or MTA3 and negative control to acquire the enriched ratio of each gene.
ORGANISM(S): Homo sapiens 
2009-08-21 | E-GEOD-14260 | biostudies-arrayexpress
TranscriptomicsExpression data from rice seedlings of wild type and the CHR729 mutant
In order to study the function of CHR729 in rice, the T-DNA insertion mutant of CHR729 was obtained and analysed. Total RNAs were extracted from 11-day-old seedlings of both wild type (Hwayoung) and CHR729 mutant plants. Affymetrix GeneChip® Rice Genome Array hybridization was performed with three b...
ORGANISM(S): Oryza sativa Japonica Group 
2010-11-04 | E-GEOD-25073 | biostudies-arrayexpress
GenomicsGenome-wide maps of H3K4me3 and H3K27me3 in HY(Hwayong) and chd1(chr729) rice.
We report the application of CHIP-seq technology for high-throughput profiling of histone modifications in HY(Hwayong) and chd1(chr729). By obtaining about 12 million reads of sequence from chromatin immunoprecipitated DNA, we generated genome-wide H3K4me3 and H3k27me3 maps of HY(Hwayong) and chd1(c...
ORGANISM(S): Oryza sativa Japonica Group 
2012-03-10 | E-GEOD-30490 | biostudies-arrayexpress
ProteomicsNucleation of DNA Repair Factors by FOXA1 Links DNA Demethylation and Transcriptional Pioneering
We report that the winged helix transcription factor FOXA1 is unexpectedly associated with components of single and double stranded-DNA repair complexes. Biochemical studies and high-throughput approaches validated the hierarchical composition of this FOXA1-nucleated machinery and revealed the depen...
ORGANISM(S): Homo sapiens (Human) 
2016-06-08 | PXD004271 | Pride
Human Lc-msms 
ProteomicsPD-L1 Mediated Immune Evasion in Triple Negative Breast Cancer Is Linked to the Loss of ZNF652
The intrinsic regulation of PD-L1 expression remains unclear. Here we report that ZNF652 is a potent transcription repressor of PD-L1. ZNF652 frequently loses heterozygosity (LOH) in various cancers. Higher LOH rate and lack of estrogen-inducible transcription lead to suppressed expression of ZNF652...
ORGANISM(S): Homo Sapiens 
2023-09-29 | PXD045945 |
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