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TranscriptomicsGenome-wide binding and mechanistic analyses of Smchd1 mediated epigenetic regulation [RNA-Seq]
Purpose: The aim of this study is to identify genes that are under the transcriptional control of the epigenetic regulator Smchd1 in neural stem cells (NSCs) derived from E14.5 mouse brain Methods: Total RNA was extracted using an AllPrep DNA/RNA Mini Kit (Qiagen) from cultured neural stem cells der...
ORGANISM(S): Mus musculus 
2015-06-11 | E-GEOD-65747 | biostudies-arrayexpress
TranscriptomicsIdentification of neural genes using Xenopus DNA microarrays
In order to isolate novel genes regulating neural induction, we utilized a DNA microarray approach. As neural induction is thought to occur via the inhibition of BMP signaling, BMP signaling was inhibited in ectodermal cells by overexpression of a dominant-negative receptor. RNAs were isolated from...
ORGANISM(S): Xenopus laevis 
2010-06-10 | E-GEOD-2266 | biostudies-arrayexpress
UnknownAtrial Functional Tricuspid Regurgitation: Contemporary Characteristics, Outcomes, and Novel Risk Score.
Not available
S-EPMC11908566 | biostudies-literature
UnknownHeparan sulfates and heparan sulfate binding proteins in sepsis.
Not available
S-EPMC9971734 | biostudies-literature
GenomicsWhole-Genome and Exome Sequencing in clear-cell Renal Cell Carcinoma (ccRCC)

Study to evaluate the molecular genetics of ccRCC through integrative analyses of tumors and tumorgrafts using multiple platforms in clinically annotated samples. Genome and exome data for patients giving consent to have the information available on a public, secure, database is being submitted.<...

phs000491.v1.p1 | EGA
UnknownProtocol for a retrospective, controlled cohort study of the impact of a change in Nature journals' editorial policy for life sciences research on the completeness of reporting study design and execution.
Not available
S-EPMC4909786 | biostudies-literature
TranscriptomicsSingle-cell RNA-seq of wild-type and Pbx1/Pbx2 double-knockout EpiSCs differentiated in vitro to pre-somitic mesoderm in the first 48 hours of differentiation.
In vertebrates, body axis elongation is fuelled by bipotent neuromesodermal progenitors (NMPs), which support the development of both spinal cord and paraxial mesoderm (PM). HOX transcription factors have been historically implicated in axial elongation, with their sequential activation playing a fu...
ORGANISM(S): Mus musculus 
2021-07-21 | E-MTAB-9774 | biostudies-arrayexpress
UnknownSynthetic anticoagulant heparan sulfate attenuates liver ischemia reperfusion injury.
Not available
S-EPMC7566620 | biostudies-literature
TranscriptomicsRNA-seq of RTS11 Macrophage-like cell line treated with Beta-glucans against untreated controls
This experiment focused on the transcriptomic responses of the rainbow trout spleen macrophage-like cell line (RTS11) in response to β-glucans (M-glucans, Biotec). RTS11 was cultured at the Scottish Fish Immunology Research Centre, University of Aberdeen. M-glucans was provided by Skretting AI. Samp...
ORGANISM(S): Oncorhynchus mykiss 
2023-03-31 | E-MTAB-12643 | biostudies-arrayexpress
UnknownFunctional genomics of epilepsy-associated mutations in the GABAA receptor subunits reveal that one mutation impairs function and two are catastrophic.
Not available
S-EPMC6463728 | biostudies-literature
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