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TranscriptomicsATAC-seq analysis of quiescent human splenic B cell populations
Memory B cells represent one of the pillar of humoral protection and are found in the circulation and secondary lymphoid organs several decades after initial pathogen or vaccine encounter. The exact cellular and biological mechanisms allowing long-term survival of quiescent cells in such a fluctuati...
ORGANISM(S): Homo sapiens 
2022-09-19 | E-MTAB-11625 | biostudies-arrayexpress
TranscriptomicsRNA-seq analysis of quiescent human splenic B cell populations
Memory B cells represent one of the pillar of humoral protection and are found in the circulation and secondary lymphoid organs several decades after initial pathogen or vaccine encounter. The exact cellular and biological mechanisms allowing long-term survival of quiescent cells in such a fluctuati...
ORGANISM(S): Homo sapiens 
2022-09-19 | E-MTAB-11622 | biostudies-arrayexpress
TranscriptomicsRNA-seq of primary human bone marrow derived mesenchymal stromal cells from pediatric B-cell acute lymphoblastic leukemia (B-ALL) patients
To investigate the identity of the tumor microenvironment in acute lymphoblastic leukemia (B-ALL), the transcriptome of mesenchymal stromal cells derived from bone marrow of three pediatric patients at the onset of the disease was analyzed and compared with its normal counterpart.
ORGANISM(S): Homo sapiens 
2021-10-16 | E-MTAB-10838 | biostudies-arrayexpress
TranscriptomicsExpression profiling of mouse bone marrow pre-B cells
Triplicate RNA-seq expression analysis of bone marrow pre-B cells isolated from mice, to demonstrate repertoire at the IgH locus Triplicate RNA-seq expression analysis of bone marrow pre-B cells
ORGANISM(S): Mus musculus 
2014-06-18 | E-GEOD-52868 | biostudies-arrayexpress
UnknownA proposal of Bursaphelenchus uncispicularis Zhuo, Li, Li, Yu & Liao, 2007 as a junior synonyms of B. yongensis Gu, Braasch, Burgermeister, Brandstetter & Zhang, 2006.
Not available
S-EPMC8015284 | biostudies-literature
ProteomicsIdentification of Ngo-B interacting proteins
Proteins interacting with Nogo-B were identified by CO-IP mass spectrometry
ORGANISM(S): Homo sapiens (Human) 
2024-07-29 | PXD046118 | Pride
Nogo-b co-ip ms 
TranscriptomicsInducible PAX5 expression in a human B lymphoblastic leukemia cell line
Hypomorphic mutations of the transcription factor PAX5 occur in one third of B-progenitor acute lymphoblastic leukemias (B-ALLs). To identify PAX5-regulated genes in B-ALL, here we employ inducible expression of PAX5 in a human B-ALL cell line (REH) that harbors a loss-of-function mutation in PAX5. ...
ORGANISM(S): Homo sapiens 
2014-06-18 | E-GEOD-57480 | biostudies-arrayexpress
TranscriptomicsPax5 restoration in a mouse model of B progenitor acute lymphoblastic leukemia
Hypomorphic mutations of PAX5 occur in one third of B-progenitor acute lymphoblastic leukemias (B-ALLs), however their functional consequences remain undefined. Here we employ advanced transgenic RNAi in mice to suppress endogenous Pax5 expression in the hematopoietic compartment in vivo, which co-o...
ORGANISM(S): Mus musculus 
2014-06-18 | E-GEOD-52870 | biostudies-arrayexpress
ProteomicsNogo-B co-IP-MS experiment in mouse liver and pancreas
Co-immunoprecipitation with either rabbit normal IgG or anti-Nogo-B antibody followed by mass spectrometry (co-IP-MS) in the liver and pancreas of wild-type C57BL/6J mice.
ORGANISM(S): Mus musculus (Mouse) 
2024-07-27 | PXD046104 | Pride
Mouse liver and pancreas 
TranscriptomicsTranscriptional profiling of mouse B cell terminal differentiation defines a signature for antibody-secreting plasma cells
Upon encounter with antigen, mature B cells undergo complex changes in their physiological state and anatomical localization, and initiate a differentiation process that ultimately produces antibody-secreting cells (ASCs), a major effector population of the immune system. To better characterize this...
ORGANISM(S): Mus musculus 
2015-04-01 | E-GEOD-60927 | biostudies-arrayexpress
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