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MetabolomicsA red wine intervention does not modify plasma trimethylamine N-oxide but is associated with broad shifts in the plasma metabolome and gut microbiota composition

BACKGROUND: Gut microbiota profiles are closely related to cardiovascular diseases through mechanisms that include the reported deleterious effects of metabolites, such as trimethylamine N-oxide (TMAO), which have been studied as diagnostic and therapeutic targets. Moderate red ...

2024-05-09 | MTBLS310 | MetaboLights
TranscriptomicsMicroarray analysis of splenic reservoir monocytes and their blood counterparts
A current paradigm states that monocytes circulate freely and patrol blood vessels, but differentiate irreversibly into dendritic cells or macrophages upon tissue entry. Here we show that bona fide undifferentiated monocytes reside in the spleen and outnumber their equivalents in circulation. The re...
ORGANISM(S): Mus musculus 
2009-08-02 | E-GEOD-14850 | biostudies-arrayexpress
UnknownBinding of CD40L to Mac-1's I-domain involves the EQLKKSKTL motif and mediates leukocyte recruitment and atherosclerosis--but does not affect immunity and thrombosis in mice.
Not available
S-EPMC3291815 | biostudies-literature
UnknownAtheroprotection through SYK inhibition fails in established disease when local macrophage proliferation dominates lesion progression.
Not available
S-EPMC4759214 | biostudies-literature
UnknownA ligand-specific blockade of the integrin Mac-1 selectively targets pathologic inflammation while maintaining protective host-defense.
Not available
S-EPMC5802769 | biostudies-literature
UnknownA randomized phase 3 trial of zanubrutinib vs ibrutinib in symptomatic Waldenstrom macroglobulinemia: the ASPEN study.
Not available
S-EPMC7596850 | biostudies-literature
UnknownImpact of Apolipoprotein A-I Infusions on Cardiovascular Events Post-MI by Neutrophil-Lymphocyte Ratio and LDL-Cholesterol Levels.
Not available
S-EPMC12059331 | biostudies-literature
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