Sort   by:  
 Page size 
TranscriptomicsOncogenic Ras inhibits IRF1 to promote viral oncolysis
Oncolytic viruses exploit common molecular changes in cancer cells, which are not present in normal cells, to target and kill cancer cells. Ras transformation and defects in type I interferon (IFN)-mediated antiviral responses are known to be the major mechanisms underlying viral oncolysis. Previous...
ORGANISM(S): Mus musculus 
2014-11-13 | E-GEOD-49469 | biostudies-arrayexpress
TranscriptomicsSuppression of IFN-induced transcription underlies IFN defects generated by activated Ras/MEK in human cancer cells
Certain oncolytic viruses exploit activated Ras signalling in order to replicate in cancer cells. Constitutive activation of the Ras/MEK pathway is known to suppress the effectiveness of the interferon (IFN) antiviral response, which may contribute to Ras-dependent viral oncolysis. Here, we identifi...
ORGANISM(S): Homo sapiens 
2012-08-02 | E-GEOD-31019 | biostudies-arrayexpress
UnknownDbx2, an Aging-Related Homeobox Gene, Inhibits the Proliferation of Adult Neural Progenitors.
Not available
S-EPMC10661760 | biostudies-literature
TranscriptomicsGene expression profile of a S. cerevisiae strain deleted in CSN5/RRI1 gene (systematic name YDL216C)
The COP9 signalosome (CSN) is a highly conserved eukaryotic protein complex which regulates the Cullin-RING family of ubiquitin ligases and carries out a deneddylase activity that resides in subunit 5 (CSN5). The budding yeast CSN is biochemically active and deletion mutants of each of its subunits ...
ORGANISM(S): Saccharomyces cerevisiae 
2013-10-23 | E-GEOD-51563 | biostudies-arrayexpress
UnknownFood insecurity, housing instability, and dietary quality among children with sickle cell disease: Assessment from a single urban center.
Not available
S-EPMC8957542 | biostudies-literature
UnknownProstaglandin E2 activates melanin-concentrating hormone neurons to drive diet-induced obesity.
Not available
S-EPMC10401019 | biostudies-literature
UnknownActivated Ras/MEK inhibits the antiviral response of alpha interferon by reducing STAT2 levels.
Not available
S-EPMC2698556 | biostudies-literature
UnknownFetal hemoglobin levels in African American and Hispanic children with sickle cell disease at baseline and in response to hydroxyurea.
Not available
S-EPMC3179608 | biostudies-literature
UnknownDose-dependent onset of regenerative program in neutron irradiated mouse skin.
Not available
S-EPMC3083422 | biostudies-literature
UnknownSuppression of IFN-induced transcription underlies IFN defects generated by activated Ras/MEK in human cancer cells.
Not available
S-EPMC3436881 | biostudies-literature
Sort   by:  
 Page size